Bitter Orange Extract

Bitter Orange Extract: Premium Natural Synephrine Powder from Kang Biotech

Through a vertically integrated supply chain, Kang Biotech gets 98% p-Synephrine (HPLC) from our controlled Citrus aurantium farms in Lianyuan, Hunan Province, to make Bitter Orange Extract that is used in medicine. Since 2011, our cGMP-certified 33,000 m² facility with 9  production lines has sent high-purity plant extracts to companies in over 40 countries. Our  water/ethanol extraction methods have been improved over 20 years of citrus processing experience to ensure batch-to-batch stability. They are certified by ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS.

What Is Bitter Orange Extract?

Our product is a solid powder made from dried, young Citrus aurantium L. (Rutaceae family) fruit that is high in phytochemicals. p-Synephrine (CAS No: 94-07-5) is a naturally occurring protoalkaloid that works by stimulating beta-3 adrenergic receptors, which is what makes the extract work.

This method increases thermogenesis and lipolysis without the heart problems that come with illegal ephedra chemicals. Our top-of-the-line 98% standard meets the requirements set by the USP and the Chinese Pharmacopoeia for pharmaceutical-grade extracts with a purity level between 6% and 98%.

The light brown-yellow powder stays stable when given in water or hydroalcoholic solutions. Because it absorbs water, it needs to be stored below 5.0% moisture.

Technical Specifications

Core Advantages for Manufacturers

The ingredients in your formula need to be clinically effective and legal. Bitter Orange Extract is used to treat three main problems:

Stability in the supply chain is guaranteed by direct farm control. Our 9 production lines can handle both small (1 kg) orders and large commercial contracts weighing many tons. We also keep a lot of stock on hand so that we can ship quickly for urgent R&D.

Getting ISO 22000, Halal, Kosher, and FAMI-QS certifications makes it easier to get into markets in the EU, North America, and the Middle East. The expert team at our company makes FDA GRAS COA and residue solvent reports.

In complex thermogenic mixtures, the extract works well with caffeine, green tea antioxidants, and L-carnitine. The pH range for softgel and fizzy release is 3.5 to 7.0.

Primary Applications

The extract's adrenergic activity powers thermogenic fat burners and metabolic support capsules. Servings of multi-ingredient weight control solutions include 10-50 mg synephrine.

Sports Nutrition: Chemical-based pre-workout supplements enhance mental focus and energy expenditure during strenuous activity. In endurance solutions, the extract acts with beta-alanine and nitric oxide precursors.

Cosmetic Industry: 2-5% extract anti-cellulite creams improve microcirculation and localized lipid metabolism. Emulsions with adequate solubilizers distribute powder nicely.

Animal Nutrition: Synephrine improves poultry and swine feed conversion rates, according to FAMI-QS certification.

Quality Assurance Process

Ingredient consistency affects brand reputation. Six quality checks are enforced by our Joint Research Center with the Hunan Institute of Agricultural Product Processing:

Raw material verification prevents Citrus species adulteration via DNA barcoding. HPLC fingerprinting confirms synephrine concentration within ±2% of specification. Heavily screened Pb, As, Cd, Hg restrictions are 50% below Prop 65.

Microbial testing with total plate counts <1,000 CFU/g follows USP <2021> guidelines. Ethanol levels meet ICH Q3C requirements using GC-MS residual solvent analysis. EU rule 396/2005 requires pesticide screening for 200+ chemicals in final COA.

Customization & OEM Services

We tailor specs to your market:

Purity Optimization: Cost objectives and label claims determine 30%, 50%, 70%, or 98% synephrine. Lower purities improve direct compression tablet flow.

Particle Engineering: 80-mesh powder is suitable for encapsulation, whereas micronized <200 mesh enhances beverage suspension stability. Spray-dried versions improve ready-to-drink water solubility.

Private Labeling: Our designers produce compliance supplement info panels and allergy statements for packaging. OEM minimum: 500 kg, 30-day lead time.

Packaging & Logistics

Standard packaging uses pharmaceutical-grade HDPE drums with dual polyethylene liners (25 kg net weight). We accommodate custom sizes from 1 kg foil bags to 500 kg bulk containers.

Transportation methods adjust to order volume: FedEx for <100 kg samples, air freight for 100-1,000 kg urgent orders, and sea freight for economical multi-ton shipments. All shipments include temperature monitoring for quality assurance.

FAQ

Q: How is it different from ephedra?

A: In adipose tissue with low beta-1/beta-2 cardiac activity, synephrine primarily targets beta-3 receptors. In contrast to ephedra's prohibited alkaloids, regular dosages do not raise blood pressure.

Q: Weight management formula dosage?

A: The average clinical trial employs 10-50 mg synephrine per serving (200-1,000 mg of 6% extract). Caffiene and other synergistic additives may necessitate dose modifications in your recipe.

Q: Do you certify allergen-free?

A: Yes. Our factory has allergen-sensitive manufacturing zones. With batch-specific testing data, we provide gluten-free, soy-free, and dairy-free declarations.

Q: How long do 500 kilogram orders take?

A: Stocked 98% ships in 5-7 business days. The manufacture and QC release of custom concentrations takes 20-25 days. Most destinations take 7-10 days by air freight.

Contact Us

Ready to secure a reliable supply of premium Bitter Orange Extract for your next formulation? Contact us today at sales02@kangbiotech.com for COA samples, pricing proposals, and custom specification consultations.