NHDC
Active ingredient: Neohesperidin Dihydrochalcone
CAS No: 20702-77-6
Specification: 98% HPLC
Grade: Food grade
Appearance: White powder
Package specification: 25 kg/drum
Mode of transportation: Express, air, or sea freight
Delivery: In stock. Small orders via FedEx; bulk orders by air or sea.
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
NHDC: High-Intensity Natural Sweetener for Food & Beverage Applications
Kang Biotech specializes in manufacturing premium-grade Neohesperidin Dihydrochalcone (NHDC) derived from citrus resources. With over 11 years of production experience and control over 20,000,000 m² of bitter orange plantations, we deliver consistent, high-purity NHDC at 98% HPLC specification. Our 33,000 m² manufacturing facility operates 9 advanced production lines, ensuring stable supply capacity and batch-to-batch consistency. Certified under ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS standards, Kang Biotech provides reliable sweetener solutions trusted by customers across 40+ countries in food, beverage, nutraceutical, and pharmaceutical industries.
What Makes NHDC a Sweetener Choice
NHDC stands out as a high-intensity sweetener approximately 1,500–1,800 times sweeter than sucrose, offering virtually zero calories. This natural derivative from neohesperidin provides clean sweetness without the bitter aftertaste common in other sweeteners.
The compound demonstrates exceptional thermal stability up to 160°C, maintaining its sweetness profile during pasteurization, UHT processing, and baking. Unlike aspartame, which degrades under heat, NHDC remains stable throughout demanding manufacturing processes.
Its pH tolerance ranges from 2 to 7, making it ideal for acidic beverages like carbonated soft drinks and fruit juices. You'll find it performs consistently across diverse formulation environments without compromising flavor quality.
Technical Specifications & Parameters
| Parameter | Specification |
|---|---|
| Botanical Source | Citrus Sinensis L. |
| Active Ingredient | Neohesperidin Dihydrochalcone |
| CAS Number | 20702-77-6 |
| Molecular Formula | C28H36O15 |
| EINECS | 243-978-6 |
| FEMA | 3811 |
| CEE Number | E959 |
| Purity | 98% HPLC |
| Grade | Food Grade |
| Appearance | White to Off-White Powder |
| Melting Point | 156-158°C |
| Standard Packaging | 25 kg/drum |
Key Functional Advantages for Your Formulations
Synergistic Sweetness Enhancement
When blended with other sweeteners like aspartame, acesulfame-K, or sugar alcohols, NHDC amplifies total sweetness by up to 40%. This synergy reduces overall sweetener costs while improving taste quality and eliminating metallic or bitter notes.
Long-Lasting Sweet Profile
The sweetness onset is slower than sucrose but extends considerably longer. This characteristic creates a more natural sweetness perception that consumers prefer over sharp, quick-fading alternatives.
Multi-Functional Benefits
Beyond sweetness, you can use very low concentrations (1-5 ppm) for effective bitterness masking. This makes it valuable for masking undesirable flavors in pharmaceuticals, protein supplements, and botanical extracts.
Low Caloric Value
The extremely low caloric content supports sugar-reduced and low-calorie product development. It's non-cariogenic and has negligible glycemic impact, making it suitable for diabetic-friendly and keto formulations.
Diverse Application Opportunities
Beverage Industry
NHDC performs excellently in carbonated soft drinks, fruit juices, sports drinks, and ready-to-drink teas. Its acid stability and heat resistance ensure consistent sweetness throughout shelf life.
Dairy & Frozen Products
Use it in yogurts, ice creams, and flavored milk to achieve desired sweetness levels while reducing sugar content. Its low-temperature stability maintains flavor integrity in frozen applications.
Confectionery & Bakery
The high heat tolerance makes it suitable for hard candies, chewing gum, cookies, and cakes. It withstands baking temperatures without degradation.
Oral Care & Pharmaceuticals
Its cooling, menthol-like finish and bitterness-masking properties enhance toothpaste, mouthwash, chewable tablets, and syrups. Low concentrations effectively mask medicinal bitterness.
Quality Assurance & Compliance Standards
Kang Biotech maintains rigorous quality control throughout cultivation, extraction, and manufacturing. Our NHDC complies with European Pharmacopoeia (EP), FCC, and USP guidelines with purity consistently ≥98%.
Quality testing includes HPLC assay verification, heavy metal analysis (Lead <3mg/kg, Arsenic <2mg/kg), microbiological safety checks (Total Plate Count <1000cfu/g), and organoleptic evaluation. Loss on drying remains <12%, ensuring product stability.
Our manufacturing systems hold ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications. NHDC carries E959 approval in the EU, GRAS status (FEMA 3811) in the USA, and listings in the Chinese Pharmacopoeia.

Frequently Asked Questions
Q: Is NHDC stable under high-temperature baking conditions?
A: Yes, it remains highly stable up to 160°C, making it suitable for baked goods and extrusion processes without sweetness loss.
Q: How does NHDC differ from Stevia in flavor profile?
A: Unlike Stevia's bitter or licorice aftertaste, NHDC provides slow-onset sweetness with a cooling finish. It's often used to mask Stevia's off-notes in blended formulations.
Q: What is the recommended dosage for bitterness masking?
A: For masking purposes, 1-5 ppm concentrations are typically sufficient. Sweetening applications require 10-50 ppm depending on your specific formulation needs.
Q: What is the shelf life and storage requirement?
A: When stored in a cool, dry place in original sealed packaging, it maintains 24 to 36 months shelf life without degradation of sweetness intensity.
Q: Can NHDC be detected via standard lab equipment?
A: Yes, it's accurately quantified using HPLC-UV detection at 282nm wavelength, ensuring precise quality verification.
Flexible Ordering & Global Delivery
Kang Biotech maintains ready stock for immediate shipment. Minimum order quantity is 1 kg, with samples available for evaluation. Small orders ship via FedEx, while bulk orders utilize air or sea freight based on your timeline requirements.
We offer OEM and ODM customization including specification adjustments, packaging design, labeling, and formulation support. Our technical team provides documentation assistance and application guidance throughout your product development process.
Partner with a Trusted NHDC Manufacturer
Ready to enhance your formulations with high-quality NHDC? Contact our experienced team for technical specifications, samples, or custom solutions. Reach us at sales02@kangbiotech.com to discuss your specific requirements today.
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