NHDC 98%
Active ingredient: NHDC (Neohesperidin Dihydrochalcone)
CAS No: 20702-77-6
Specification: 98% HPLC
Grade: Food grade
Appearance: White powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air cargo, sea cargo
Delivery: Ready inventory for fast shipment worldwide.
Minimum order quantity: 1 kg, sample orders supported.
- Free Samples
- Quality Assurance
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Product Introduction
NHDC 98%: Premium High-Intensity Sweetener from Kang Biotech
Kang Biotech produces pharmaceutical-grade NHDC 98% (Neohesperidin Dihydrochalcone) with ≥98.0% HPLC purity. Our product, made from citrus bioflavonoids and catalytic hydrogenation, is 1,500–1,800 times sweeter than sucrose. We have 11 years of manufacturing experience and 20,000,000 m² of controlled bitter orange plantations in Hunan Province. Our ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certified production methods assure batch-to-batch consistency. Our 9 modern extraction lines in our 33,000 m² facility ensure steady supply for worldwide food, pharmaceutical, and feed applications.

What Makes NHDC 98% a High-Performance Sweetener?
Our product intensifies sweetness and taste. The chemical formula C28H36O15 (CAS No. 20702-77-6, FEMA 3811, E959) tackles sugar-reduced system formulation issues.
Saccharin and acesulfame-K's metallic aftertastes are well-masked by the combination. At low doses, it neutralizes plant protein, caffeine, and active pharmaceutical ingredient bitterness without adding sweetness.
Its slow-onset profile cools like menthol. Beverages, dental care products, and nutraceuticals that need longer taste release benefit from this.
Technical Specifications
| Parameter | Specification |
|---|---|
| Botanical Source | Citrus Sinensis L. |
| Active Ingredient | Neohesperidin Dihydrochalcone |
| Purity | 98% HPLC |
| Molecular Formula | C28H36O15 |
| CAS Number | 20702-77-6 |
| EINECS | 243-978-6 |
| FEMA Number | 3811 |
| EU E-Number | E959 |
| Appearance | White to Off-white Powder |
| Melting Point | 156-158°C |
| Loss on Drying | ≤12% |
| pH Stability Range | 2.0–7.0 |
| Sweetness Intensity | 1,500–1,800× Sucrose |
Core Advantages for Industrial Applications
Thermal and Chemical Stability
Without deterioration, our product can endure UHT pasteurization, baking (up to 200°C), and acidic conditions (pH ≥2.0). This stability reduces high-temperature industrial reformulation hazards.
Sweetness Synergy
When mixed with stevia, erythritol, or monk fruit extract, it cuts sweetener use by 20–40%. This decreases formulation costs and tastes sugarier.
Bitterness Masking Below Threshold
At 1–5 ppm, it hides bitterness without adding sweetness. Pharmaceutical syrups and protein-fortified drinks require it.
Non-Caloric Effect
Use (5–50 ppm) contributes little calories, supporting clean-label and low-calorie product claims.
Industrial Application Scenarios
Functional Beverages
NHDC 98% compensates for caffeine bitterness and vitamin B complexes in sugar-free energy beverages and restores mouthfeel. Usually 10–30 ppm with stevia or sucralose.
Pharma Formulations
Hard mineral and API astringency is hidden by 5–20 ppm liquid syrups and chewable tablets. When pre-dissolved in propylene glycol, its water solubility provides uniform dispersion.
Food for animals
Feed-grade solutions make piglet and calf starting meals more tasty. It remains effective at 50–100 ppm inclusion rates after pelleting (150–180°C).
Bakery and Dairy
Reduces sugars while sweetening yogurt, ice cream, and cookies. Heat resilience makes it ideal for long-oven baked items.
Quality Control Systems
Kang Biotech uses many quality checks:
Assurance of purity
Using HPLC, every batch is confirmed to be ≥98.0% pure. Remaining neohesperidin is monitored below 0.5%.
Heavy Metal Screening
USP/EP-compliant testing guaranties Lead (Pb) <2 ppm, Arsenic (As) <2 ppm, and Mercury (Hg) <0.1 ppm.
Microbiological Safety
Plate count <1,000 cfu/g, Yeast/Mold <100 cfu/g, negative for E. coli and Salmonella.
Verifying Solubility
Manufacturing compatibility in liquid and powder applications is confirmed by dispersion tests in water (40°C) and ethanol.

Packaging and Logistics
Standard packaging: 25 kilogram food-grade polyethylene-lined fiber drums.
Custom packaging for 1 kilogram, 5 kg, and 10 kg.
Worldwide Shipping:
- Express (FedEx/DHL): 5–7 days for samples
- Air freight: big orders 10–15 days.
- Affordable container freight by sea.
1 kilogram minimum order (samples supported).
Ready stock ships within 48 hours after purchase confirmation.

FAQ
Q: How thermally stable is it compared to aspartame?
A: It outperforms aspartame, especially in acidic and high-heat environments when it breaks down. Full activity of NHDC remains after UHT (138°C, 4 seconds).
Q: Can it stand alone as sweetener?
A: Technically conceivable, its slow-onset sweetness and cooling aftertaste make it best as a co-sweetener or flavor modifier at 5–30% of total sweetener mixes.
Q: What is the recommended dosage for bitterness masking?
A: In drinks and syrups, 1–5 ppm masks without sweetness. Pharma applications may need 10–20 ppm depending on API bitterness.
Q: Does it dissolve in cold water?
A: Sparingly. Before dilution, dissolve in hot water (60–80°C) or ethanol/propylene glycol (10%) for thorough dispersion.
Q: Is there a caloric impact?
A: At usual usage levels (5-50 ppm), caloric contribution is insignificant (<0.1 kcal per serving), ensuring "zero calorie" labeling compliance.
Contact Us
For NHDC 98%, you can request COA, MSDS, or application guidelines for your specific formulation needs. Our technical team provides customized solutions for beverage, pharmaceutical, and feed applications. Email: sales02@kangbiotech.com
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