Flavanone Compound

High-Purity Flavanone Compound from Kang Biotech – Reliable Citrus Extract for Industrial Applications

Kang Biotech extracts Citrus aurantium L. using advanced water and ethanol to produce  Flavanone Compound (Naringenin) with 98% purity via HPLC. With 11 years of citrus extraction experience and 20,000,000 m² of self-managed bitter orange farms, we guaranty consistent batch-to-batch supply year-round. Our 33,000 m² manufacturing facility has 9 specialized lines and is accredited to ISO 22000, HACCP, Halal, Kosher, and FAMI-QS standards. All product kilograms undergo stringent ICP-MS heavy metal screening (<0.1 ppm) and GC-MS residual solvent testing, fulfilling ICH Q3C standards for worldwide pharmaceutical and nutraceutical compliance.

What Is Flavanone Compound and Why It Matters to Your Formulation?

A product with a 2,3-dihydro-2-phenylchromen-4-one backbone is a flavonoid without a C2-C3 double bond. Naringenin and hesperetin, mostly from citrus peels, are most economically important.

Distinct structure makes molecule thermally stable compared to anthocyanins, withstanding UHT processing up to 120°C. Bioavailability-critical applications benefit from its greater lipophilicity and cellular membrane permeability than flavones. DMSO and hot ethanol dissolve raw product better than aqueous solutions, however water solubility is a problem.

Industrial customers face limited oral supplement bioavailability, quick first-pass hepatic metabolism, and beverage precipitation concerns. Advanced glycosylation or cyclodextrin complexation eliminates these difficulties, releasing antioxidant and anti-inflammatory potential in food, medicinal, and cosmetic applications.

Technical Specifications and Properties

Our product demonstrates distinct UV-Vis spectroscopy profiles, lacking the Band I absorption (300–380 nm) typical of flavones—a rapid lab distinction method. The (S)-enantiomer configuration ensures optimal bioactivity, critical for pharmaceutical-grade applications.

Industrial Applications Across Multiple Sectors

Nutraceuticals and Pharmaceuticals

Pharmaceutical formulations that address metabolic syndrome and chronic venous insufficiency use high-purity product as an active ingredient. For capsule and tablet bioavailability, your buyers need stomach acid-resistant crystalline forms. The product is devoid of flavones and chalcones per USP/EP standards.

Food and Drink Additives

As an antioxidant and bitter blocker, citrus-based drinks use Flavanone Compound. Pasteurization (70–90°C) does not affect taste characteristics or precipitate the chemical. Using cyclodextrin complexation in aqueous environments can solve solubility issues.

Beauty Formulations

Its photo-stability and tyrosinase suppression enable UV-damaged creams. For deep dermal skin regeneration and brightening, our product works with oil-in-water (O/W) emulsions.

Interactions

The combination of hesperetin and naringenin increases radical scavenging by 35–40% in industry experiments. Our product works well in multi-component supplements.

Rigorous Quality Control Standards

Kang Biotech's quality assurance methodology covers all important controls:

Validated HPLC-DAD against international reference standards assures >98% naringenin with no flavones.

Residual Solvent Testing: Pharmacy compliance requires GC-MS to certify ethanol and methanol levels below 5000 ppm per ICH Q3C recommendations.

ICP-MS technique detects lead, arsenic, cadmium, and mercury at <0.1 ppm, exceeding regional limits to identify heavy metals.

Chiral Purity Verification: Racemic combinations impair treatment effectiveness by 50%, hence enantiomer-specific analysis ensures the bioactive form (S).

Tests show total aerobic bacteria count is below 1000 CFU/g, fulfilling EU and FDA food safety standards. Before shipping, batches are sterile-tested.

Processing Capabilities and Customization

Water- and ethanol-based extraction provides versatile application optimization. Alcohol extraction yields the most for pharmaceutical-grade purity, whereas water extraction is best for food-grade clean-label applications.

OEM/ODM Services: We create specifications (90–99% purity), packaging (1 kilogram foil packets to 25 kg fiber drums), and labeling to suit regional regulatory standards. Fully traceable private labeling contains your brand identification.

From 1 kg for R&D samples to multi-ton commercial orders. Our 9 production lines offer fast turnaround in 7–10 days for stock products.

Packaging and Logistics

Standard Packaging: 25 kg fiber drums with double food-grade PE inner bags. Custom packaging available from 1 kg to 1000 kg formats.

Global Shipping Options: FedEx express (3–5 days), air freight (7–10 days), or sea freight for bulk orders. We maintain ready stock at our Hunan facility for immediate dispatch.

Documentation: Each shipment includes Certificate of Analysis (CoA), MSDS, allergen statements, and BSE/TSE-free declarations. Country-specific regulatory documents provided upon request.

FAQ

Q: How do water and organic solvents affect product solubility?

A: The chemical dissolves well in DMSO and hot ethanol but poorly in water. For stable dispersion in aqueous environments, we propose cyclodextrin complexation.

Q: Can the product resist UHT processing?

A: It's stable at 120°C. However, prolonged exposure above this temperature may cause chalcone ring-opening, changing bioactivity.

Q: What is your standardized extract's shelf life?

A: Our solution stays 98% potent for 24–36 months in closed containers away from light at ambient temperature.

Q: How do you identify product from flavone in the lab?

A: UV-Vis spectroscopy quickly distinguishes flavonones from flavones because they lack Band I absorption (300–380 nm).

Q: Are there synergies when merging products?

A: Yes. Industry research suggests hesperetin-naringenin mixes boost antioxidant activity by 35%.

Contact Us

Partner with Kang Biotech for reliable, certified Flavanone Compound supply backed by 11 years of citrus extraction leadership. Request samples or technical specifications today: sales02@kangbiotech.com.