Citrus Reticulata Flavonoid
Citrus Reticulata Flavonoid

Citrus Reticulata Flavonoid

Production process: Water extraction / Ethanol extraction
Active ingredient: Nobiletin
CAS No: 478-01-3
Specification: 98% HPLC
Grade: Food grade
Appearance: Fine white to off-white powder
Package specification: 25kg/drum
Mode of transportation: Express, air freight, or sea freight
Delivery: In-stock supply ensures prompt shipment. FedEx is used for small quantities, while large-volume orders are shipped by air or sea.
OEM/ODM: Available
Minimum order quantity: 1kg, sample orders accepted
  • Free Samples
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  • 24/7 Customer Service

Product Introduction

Citrus Reticulata Flavonoid – Premium Polymethoxyflavone Extract from Kang Biotech

Kang Biotech was founded in 2011 and makes pharmaceutical-grade Citrus Reticulata Flavonoid from citrus peel using  methods for both water and ethanol extraction. Our product has 98% Nobiletin (HPLC), which has been standardized to provide consistent polymethoxyflavone content that is better absorbed by the body. We promise consistent quality from batch to batch and a steady supply capacity because we have been extracting citrus fruits for over 11 years and are in charge of 20,000,000 m² of bitter orange farms in Hunan Province. Our 33,000 m² integrated production center has 9 high-tech production lines that are approved by ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS. We keep goods in stock so that they can be sent quickly by FedEx, air, or sea freight to more than 40 countries around the world.

What Makes Citrus Reticulata Flavonoid Different?

Citrus Reticulata Flavonoid is a specific group of methylated flavones that come from fresh mandarin peel (Citrus reticulata Blanco). Unlike other citrus extracts, our formula focuses on polymethoxyflavones with high concentrations, such as Nobiletin and Tangeretin.

These methylated structures are better at sticking to fat than antioxidants that aren't modified. This improves cellular function and absorption in the intestines. In the end, they came up with a natural ingredient that works well in a number of different situations.

Our production process keeps the full profile of flavonoids while reaching levels of purity that are suitable for medicinal use. This makes sure you get a clean-label ingredient whose stability and performance have been proven.

Technical Specifications

Parameter Specification
Botanical Source Citrus reticulata Blanco / Citrus sinensis L.
Active Ingredient Nobiletin (Polymethoxyflavones)
CAS Number 478-01-3
Molecular Formula C₂₈H₃₄O₁₅
EINECS Number 236-216-14
Purity Range 10%–98% HPLC
Standard Grade 98% HPLC (Nobiletin)
Appearance Fine white to off-white powder
Extraction Method Water extraction / Ethanol extraction
Package Size 25 kg/drum (custom packaging available)
Grade Food grade / Nutraceutical grade
Minimum Order 1 kg (samples accepted)

Key Functional Properties

For your recipes to work, the elements must be reliable in the real world. Our flavonoid extract is very stable at high temperatures, keeping its bioactivity at up to 120°C while it is being processed.

Polymethoxyflavones are very good at mixing with both water-loving and fat-loving materials because they are very lipophilic. This adaptability makes it possible for a wide range of application forms, from drinks to pills.

ORAC testing proved that our product has strong antioxidant properties. The methylated structure makes the bioflavonoids more stable against oxidation than regular orange bioflavonoids. This makes finished goods last longer on the shelf.

Formulation strategies can be used to control the bitter taste profile. We offer expert support to help you improve taste while keeping the product's functionality.

Professional Application Scenarios

Metabolic Health Supplements: Our high-purity extract is put into capsules and tablets that help control lipids and improve insulin sensitivity. Because polymethoxyflavones are more bioavailable, they have clear benefits in biologically complex settings.

Functional Beverage Systems: Our element stays stable in acidic conditions (pH 2.5–4.0) without forming crystals. Because of this, it works great for isotonic drinks, improved water products, and fitness drinks that need to be clear and consistent.

Advanced Cosmetic Formulations: The ingredient's ability to improve skin microcirculation is good for serums and creams that are put on the skin. Our flavonoid extract stays active even when it's exposed to UV light and air in emulsion systems, while many botanical antioxidants break down quickly.

Nutraceutical Powders and Blends: The small particles make sure that mixtures of many ingredients are spread out evenly. Our uniform strength makes sure that dosing is the same from one production batch to the next.

Quality Control Standards

High-Performance Liquid Chromatography is used to make fingerprints of the raw materials as the first step in quality assurance. We measure Nobiletin, Tangeretin, and Hesperidin to make sure the species is real and stop it from being tampered with.

Comprehensive testing procedures are used on every batch:

Purity Verification: HPLC research shows that the amount of polymethoxyflavone meets the standards set by the specification.

Safety Screening: ICP-MS research makes sure that heavy metals like Pb, As, Hg, and Cd stay below international standards, such as those set by Prop 65 and the EU.

Analysis of Pesticides: GC-MS/LC-MS screening looks for more than 500 chemicals, meeting both organic and common standards.

Tests for Microbes: USP and EP guidelines are followed for total aerobic numbers and pathogen screens.

Documentation of Stability: Both short-term and long-term tests confirm the shelf life under certain storage conditions.

Through advanced analytical methods, our Joint Research Center with the Hunan Institute of Agricultural Product Processing makes sure that quality is always getting better.

Quality Control Standards

Why Choose Kang Biotech as Your Supplier?

You need a partner who knows how to find ingredients technically. Our fully linked supply chain manages every step, from growing the plants to putting them in boxes.

With more than 20 years of professional experience in citrus extraction, our team can help you with your unique formulation problems. We keep a collection on hand so that we can quickly fill both trial orders and large-scale business needs.

We are committed to meeting world quality standards, as shown by our many certificates, including ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS. We meet the regulatory needs of markets around the world, whether you need materials that are food-grade, pharmaceutical-grade, or feed-grade.

You can change the specs, packaging, and labels with OEM and ODM services. Your regulatory filings and product development deadlines will be helped by our expert documentation.

 ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS.

FAQ

Q: How does this extract differ from standard Citrus Aurantium products?

A: Our Citrus reticulata source has more polymethoxyflavone, especially Nobiletin. This supports metabolic and cognitive function more than synephrine-dominant Aurantium extracts.

Q: High-purity grades' aqueous solubility?

A: Pure polymethoxyflavones are lipophilic. Micro-encapsulated or spray-dried versions containing cold-water dispersible maltodextrin are available for beverages.

Q: Does this component tolerate high-heat food processing?

A: The flavonoid structure is stable at ordinary extrusion temperatures. Process-specific matrix compatibility testing is advised.

Q: Does this meet EU Novel Food regulations?

A: Many governments use citrus peel extracts as culinary additives. Check your target market's newest EFSA catalogs for high-purity isolates.

Q: What dose range is clinically effective?

A: For metabolic support, industry pharmacokinetic studies recommend 100–500 mg daily of standardized 40–60% PMF extracts confirmed by human clinical trials.

Contact Us

Ready to source pharmaceutical-grade Citrus Reticulata Flavonoid backed by manufacturing? Contact our technical team at sales02@kangbiotech.com for specifications, samples, and application support tailored to your formulation needs.