Flavone Compound
Active ingredient: Apigenin
CAS No: 520-36-5
Specification: 98% HPLC tested
Grade: Food grade
Appearance: Light yellow to yellow powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air shipment, sea shipment
Delivery: Stable stock supply with flexible shipping methods. Small orders via FedEx, bulk orders by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Flavone Compound – High-Purity Natural Antioxidant Ingredient from Kang Biotech
Kang Biotech extracts Citrus aurantium L. using advanced water or ethanol to create superior Flavone Compound (Apigenin, CAS No. 520-36-5) with 98% HPLC purity. Our facility, with 11 years of manufacturing experience and a technical staff with 20+ years of citrus extraction competence, spans 33,000 m², 9 modern production lines, and 20,000,000 m² of controlled bitter orange farms. Our integrated manufacturing chain provides batch quality, stable supply, ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications. To satisfy worldwide pharmaceutical and food-grade requirements, each batch is rigorously quality-verified.
What Is Flavone Compound?
Flavonoids with a 2-phenylchromen-4-one backbone are our product. Instead of a C3 hydroxyl group, it has a double bond between C2 and C3.
Plants manufacture polyphenolic chemicals. Bioactive compounds in functional applications are powerful.
Orange plants are structurally modified to produce apigenin, our product's active ingredient. Providing a natural alternative to synthetic antioxidants like BHA and BHT and enhanced thermal and oxidative stability in formulations meets industrial objectives.
Technical Specifications and Physical Properties
Our product (Apigenin) meets stringent technical and safety standards required by international markets.
| Parameter | Specification |
|---|---|
| Botanical Source | Citrus aurantium L. |
| Active Ingredient | Apigenin |
| CAS Number | 520-36-5 |
| EINECS Number | 236-216-9 |
| Molecular Formula | C₂₈H₃₄O₁₅ |
| Purity | ≥98% HPLC tested |
| Appearance | Light yellow to yellow powder |
| UV Absorption | 300–350 nm (Band I), 240–285 nm (Band II) |
| Melting Point | >200°C |
| Solubility | Soluble in DMSO, ethanol, methanol; poorly water-soluble |
| Grade | Food grade |
| Package | 25 kg/drum |
The chemical is thermally stable at 150–180°C during short-term processing. It may be used for spray drying and encapsulating at high temperatures.
Distinct UV absorption characteristic allows spectral analysis for identity verification and quality control.
Functional Benefits of Flavone Compound
Our product is highly regarded in the nutraceutical, food, and cosmeceutical sectors due to its multi-functional qualities.
Strong Antioxidant Activity
DPPH and ORAC experiments show its remarkable free radical scavenging activity. Lipid-rich and omega-3-fortified goods are protected from oxidative destruction by this action.
Favourable Stability
Unlike anthocyanins, our product resists photo-degradation and is potent under changing storage circumstances. It is stable in acidic (pH 3.0–5.0) settings, making it appropriate for carbonated and functional drinks.
Clean Label Appeal
Consumer desire for clean label products is met by this plant-derived natural ingredient. You can trust this bio-based antioxidant to replace synthetic ones.
Metallic Chelation
The chemical prevents metal-catalyzed oxidation in complex food systems and extends product shelf life by chelating metal ions like Fe²⁺ and Cu²⁺.
Quality Control and Testing Standards
Production and testing at Kang Biotech follow pharmaceutical-grade quality standards.
Verifying HPLC
HPLC with UV-Vis or DAD detection is performed on every batch. This confirms active flavone content satisfies ≥98% and identifies contaminants.
Safety Testing
We use LC-MS/MS to identify pesticide residues and mycotoxins. To meet worldwide safety regulations, ICP-MS analyzes lead, arsenic, cadmium, and mercury.
Standardizing antioxidant potency
Folin-Ciocalteu measures TPC. This provides constant antioxidant potency and activity across batches.
Microbe Limits
Total Plate Count, Yeast & Mold, and E. coli are strictly limited by microbiological tests. This guarantees pharmaceutical-grade ingredients for specific applications.

Applications Across Industries
Flavone Compound is used in bioactive and stable high-performance settings.
Nutritional Supplements
Liposomal Apigenin passes the blood-brain barrier in neuroprotective formulations. In supplements, it promotes cognitive health, relaxation, and stress response.
Functional Foods and Drinks
It naturally stabilizes lipid-rich emulsions and omega-3-fortified goods, preventing rancidity. It works for carbonated functional drinks and ready-to-drink wellness drinks because to its pH stability and heat resilience.
Pharmaceutical Formulations
Our product inhibits collagenase and elastase in advanced anti-aging serums. This prevents UV-induced premature aging of the skin matrix and preserves complex aqueous-oil formulation performance.
Animal Food and Nutrition
This feed ingredient boosts antioxidant levels and general health in cattle and companion animals.
Packaging, Delivery, and Customization
Kang Biotech has a range of flexible logistics options to meet the needs of your business.
Every package comes with 25 kg of fiber drums.
Orders must be at least 1 kg, and samples can be sent for testing.
You can choose FedEx for small items or air or sea freight for large ones.
Stock Availability: Stable stock guaranties quick turn-around times
OEM/ODM Services: Specifications, purity levels, package design, labeling, and formulation help can all be changed to fit your needs.
Our streamlined supply chain, which includes everything from growing the crops to delivering them to over 40 countries around the world, guaranties uniform quality and on-time delivery.

FAQ
Q1: How can glycosylation impact product efficacy?
A: Bioavailability may decrease when glycosylation increases water solubility. More lipophilic aglycones like Apigenin are easily absorbed throughout cell membranes.
Q2: What is the thermal stability limit during spray drying?
A: Many flavones are stable at 150–180°C for short periods. Continuous heat exposure might cause oxidative deterioration, hence regulated processing is advised.
Q3: Is the product suitable for acidic drinks?
A: Indeed, it is stable at pH 3.0–5.0. Carbonated functional drinks and acidic juices benefit from it.
Q4: How do I keep product to maintain potency?
A: Keep cool in sealed, light-resistant containers below 25°C. Photo-oxidation is prevented, ensuring long-term stability.
Q5: Does the product interact with metal ions?
A: This chelates metal ions like Fe²⁺ and Cu²⁺. This inhibits metal-catalyzed oxidation but may generate complicated color alterations that need formulation control.
Contact Us
Ready to integrate high-purity Flavone Compound into your formulations? Contact our team today for technical support, samples, or customized solutions.
Email: sales02@kangbiotech.com
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