Nobiletin Citrus Peel Extract
Nobiletin Citrus Peel Extract

Nobiletin Citrus Peel Extract

Production process: Water extraction / Ethanol extraction
Active ingredient: Nobiletin
CAS No: 478-01-3
Specification: 98% HPLC
Grade: Food grade
Appearance: White to creamy off-white powder
Package specification: 25kg/drum
Mode of transportation: Express delivery, air freight, marine shipping
Delivery: Adequate stock ensures timely fulfillment. Small-quantity orders are shipped by FedEx, while bulk orders are transported via air or sea freight.
OEM/ODM: Available
Minimum order quantity: 1kg, sample orders are supported
  • Free Samples
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Nobiletin Citrus Peel Extract – Premium Polymethoxyflavone Ingredient

Kang Biotech provides HPLC-analyzed pharmaceutical-grade Nobiletin Citrus Peel Extract with specified purity up to 98%. Our extract is extracted from quality Citrus sinensis using innovative water and ethanol methods in our 33,000 m² accredited facility, supported by over 20,000,000 m² of managed citrus orchards. We guarantee batch quality and worldwide compliance with 11 years of production experience and ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications. Our manufacturing capability provides stable supply and flexible OEM/ODM customization for nutraceutical, functional food, and cosmeceutical applications in 40+ countries.

What Is Nobiletin Citrus Peel Extract?

The PMF family includes 5,6,7,8,3',4'-hexamethoxyflavone, which is found in product. This chemical is found in citrus exocarp, notably Orange (Citrus sinensis) and other kinds.

This extract overcomes bioavailability issues with its completely methylated structure, unlike hydroxylated flavonoids. Lipophilic characteristics improve blood-brain barrier permeability and cellular membrane penetration.

This ingredient solves formulation issues for natural, non-toxic metabolic wellness and neuroprotection agents. Standardized extracts replace raw citrus powders with quantifiable actives.

Technical Specifications & Properties

Our product delivers precise technical parameters for professional formulation requirements.

Parameter Specification
Active Ingredient Nobiletin
CAS Number 478-01-3
Molecular Formula C21H22O8
Botanical Source Citrus sinensis L.
Purity Range 10%-98% HPLC
Appearance White to creamy off-white powder
EINECS Number 236-216-14
Solubility Lipophilic, low water solubility
Thermal Stability High (suitable for heat processing)

The extract presents exceptional metabolic stability due to its high degree of methoxylation. This structural advantage provides resistance to first-pass metabolism, outperforming common flavonoids like quercetin in bioactivity retention.

Physical characteristics include fine particle structure and high thermal stability, making it compatible with high-temperature processing in functional food manufacturing. Specialized delivery systems are available for aqueous applications requiring water-dispersible grades.

Quality Control & Compliance

Kang Biotech prioritizes purity, potency, and safety in quality assurance.

HPLC-DAD fingerprinting verifies polymethoxyflavone botanical authenticity. To fulfill EU and FDA regulations, each production batch is pesticide residue screened for over 500 chemicals.

The worldwide limitations for lead, arsenic, cadmium, and mercury are monitored by heavy metal analysis. Microbial testing meets USP <61>/<62> criteria for total plate count, yeast, mold, and harmful bacteria.

GC-MS solvent residue measurement verifies extraction media are under ppm limitations. Our ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS-certified production processes provide product traceability from raw material selection to delivery.

This strict methodology assures Nobiletin Citrus Peel Extract fulfills pharmaceutical-grade safety and effectiveness standards.

Quality Control & Compliance

Professional Application Scenarios

Supplements and Nutraceuticals

Cognitive health formulations benefit from the product's CREB signaling enhancement. It regulates adiponectin and activates AMPK pathways to support metabolic health complexes.

Formulators add this component to weight-management and aging-support products. Stability in physiological contexts ensures effectiveness under difficult diets.

Food Innovation with Function

Thermal stability allows the extract to be used in beverages, nutrition bars, and fortified meals. Active material is preserved throughout pasteurization and baking at high temperatures.

Water-dispersible grades with HPBCD complexation or micro-emulsification help beverage makers create clear solutions.

Cosmetic Uses

Premium skincare products use this substance to inhibit tyrosinase and decrease UV-induced MMP-1. It maintains anti-inflammatory activity in complicated emulsion-based topicals.

Professional cosmeceutical brightening, anti-aging, and protective skincare products benefit from the extract.

Supply Chain & Delivery Capabilities

Kang Biotech keeps enough stock to meet trial and commercial orders quickly. Our minimum order quantity is 1kg for R&D and pilot manufacturing.

FedEx expedites international small-quantity orders. Air or sea freight is used for bulk business orders depending on volume and timeframe.

Standard packing is 25kg/drum. OEM/ODM services provide labeling, size, and branding for custom packaging.

Direct manufacturer control over farming and production ensures supply chain stability. The Hunan Institute of Agricultural Product Processing and our research center collaborate to increase quality and innovate.

Supply Chain & Delivery Capabilities

FAQ

Q: What distinguishes Citrus Peel Extract from Citrus Aurantium?

A: Standardizes polymethoxyflavones (Nobiletin/Tangeretin) for metabolic health in citrus peel extract. Citrus Aurantium weight management formulas emphasize Synephrine.

Q: Is water-soluble grade for beverages?

A: Yes. We provide HPBCD complexed or micro-emulsified water-dispersible extracts for clear beverage systems.

Q: Agriculture pesticide residue control: how?

A: Every production batch in our managed plantation supply chain undergoes Eurofins laboratory 390-item pesticide residue screening.

Q: Has pasteurization affected active content?

A: Polymethoxyflavones retain over 98% potency after HTST pasteurization in beverage and food processing.

Q: What is the proper storage shelf life?

A: When sealed and kept cold, dry, and out of direct light and moisture, the extract lasts 24 months.

Contact Us

Ready to integrate premium Nobiletin Citrus Peel Extract into your formulations? Contact our technical team at sales02@kangbiotech.com for samples, specifications, and customized solutions tailored to your application requirements.