Naringenin 480-41-1
Naringenin 480-41-1

Naringenin 480-41-1

Production process: Water extraction / Ethanol extraction
Active ingredient: Naringenin
CAS No: 480-41-1
Specification: 98% HPLC
Grade: Food grade
Appearance: White powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Sufficient stock available. Small orders via FedEx, while large orders can be shipped by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
  • Free Samples
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

High-Purity Naringenin 480-41-1 | Citrus-Derived Flavanone Supplier 

Pharmaceutical-grade Naringenin 480-41-1 from Kang Biotech is 98% pure (HPLC verified). It is extracted from Citrus aurantium L. using contemporary water and ethanol techniques. We manage the whole supply chain, from our 20,000,000 m² Hunan Province bitter orange orchards to our 33,000 m² GMP-compliant production center. We have over 20 years of citrus extraction technological knowledge and 11 years of product manufacturing.

Our ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications support our manufacturing capacity and batch uniformity. We stock plenty for testing (1 kg) and corporate usage and provide OEM/ODM customisation to fit your formulation needs.

ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications

Technical Specifications

Parameter Details
Botanical Source Citrus aurantium L.
Active Ingredient Naringenin
CAS Number 480-41-1
Molecular Formula C₁₅H₁₂O₅
Molecular Weight 272.25 g/mol
Specification 98% (HPLC)
Appearance Off-white to light yellow crystalline powder
Melting Point 247–250°C
Grade Food grade / Pharmaceutical grade
Package 25 kg/drum (customizable)
MOQ 1 kg (samples available)
Storage Store in a tightly sealed, light-resistant container at controlled room temperature

What Makes Our Naringenin 480-41-1 Different?

Our product is the aglycone form of naringin, a flavanone that is found naturally in cherry tomatoes, oranges, and grapefruit skin. Naringenin is more bioavailable than its glycoside cousin because the sugar molecule doesn't need to be broken down by enzymes. In this way, it is fit for uses that need high biological activity and quick absorption.

We get our product from Citrus aurantium using tested methods that keep the molecules' structure. Our HPLC analysis makes sure that the product is at least 98% pure, and we keep a close eye on the moisture content (LOD ≤1.0%) and heavy metal residues to make sure they follow the rules set by ICH Q3C.

The organic origin of our product is safe to use because it has been tested for Carbon-14 and comes with full certificates of analysis. This guaranties that you will get an ingredient that comes from natural sources and meets the strictest international standards for use in medicine and nutrition.

Rigorous Quality Control You Can Rely On 

Quality assurance is non-negotiable when sourcing high-purity flavonoids. Naringenin 480-41-1 from us is tested in several steps to make sure it is safe, pure, and consistent.

HPLC is used for purity testing to make sure that related chemicals like naringin or hesperetin are not present. ²H-NMR and LC-MS are used to confirm the molecular fingerprint and make sure the structure is correct.

Safety testing includes Heavy Metal Screening (ICP-MS) for arsenic, lead, mercury, and cadmium, Total Plate Count, Yeast, and Mold, and Residual Solvent Testing (GC) to meet ICH Q3C requirements.

We also measure particle size distribution (PSD) to make sure that the dissolution rates in your end formulas are as good as they can be. This strict process makes sure you get a reliable ingredient that works the same way in all batches, which lowers formulation risks and regulatory concerns.

Rigorous Quality Control

Versatile Applications Across Multiple Industries

Our  bioactive chemical is employed in three primary areas:

It is a lead molecule for metabolic syndrome and type 2 diabetes research in pharmaceuticals. It affects glucose absorption and fat burning. It helps create novel drugs by targeting several cellular targets.

Advance Nutraceuticals: Cardiovascular support supplements with naringenin restrict LDL oxidation and dilate blood arteries. Functional food firms who wish to boost metabolic health employ it since it works reliably in acidic digestive conditions.

Naringenin inhibits UV-induced oxidative stress and collagen degradation in anti-aging skin care. Good skin penetration and long-term photostability make it more effective than synthetic antioxidants. High-end cosmetic businesses who desire effective natural active ingredients would love it.

Whether it's a pill, drink, skin cream, or other product, our experts can help you prepare for optimal solubility and stability.

Why Choose Kang Biotech as Your Naringenin Supplier?

Control Over the Entire Manufacturing Process: We are in charge of every step, from growing the plants to extracting the oil. This gives us control over quality and traceability that third-party suppliers can't match.

We can do advanced research and development because our Joint Research Center with the Hunan Institute of Agricultural Product Processing helps us come up with new ways to extract resources and make products all the time.

Customization that is easy to work with: OEM/ODM services include specs, packing, labeling, and formulation help that are made to fit your legal needs and market place.

Global Compliance: We have licenses for food, pharmaceuticals, feed, and halal/kosher norms, which makes it easy to enter the markets of more than 40 countries.

Dependable Supply Chain: We make sure you get your samples on time whether you need 1 kg or multiple tons. We have enough stock and offer multiple shipping options, such as FedEx for small orders and air/sea freight for bulk orders.

Why Choose Kang Biotech as Your Naringenin Supplier

Packaging & Delivery

We offer standard packaging in 25 kg/drum with options for custom packaging sizes to match your production needs. Our logistics team provides flexible shipping solutions: small trial orders ship via FedEx for quick delivery, while bulk orders benefit from cost-effective air or sea freight options.

All shipments include complete documentation—Certificate of Analysis, Safety Data Sheet, and origin certificates—to facilitate customs clearance and regulatory compliance in your destination market.

FAQ

Q: What distinguishes the product from Naringin?

A: Naringenin is the aglycone, naringin the glycoside. Naringenin's quicker absorption and increased biological activity are due to its lack of enzymatic sugar moiety cleavage.

Q: How should the product be stored?

A: To avoid oxidative deterioration and ensure long-term stability, store it in a well sealed, light-resistant container at regulated room temperature.

Q: What about liquid formulations' limited water solubility?

A: To improve solubility, use PEG-400, ethanol, solid dispersions, or nano-emulsions. Our technical staff can advise on formulation for your application.

Q: Any contraindications?

A: Naringenin inhibits CYP450 enzymes (CYP3A4), thus formulators should consider drug-nutrient interactions when making combination products.

Q: Is the product source natural or synthetic?

A: Carbon-14 testing and botanical origin certifications verify our Citrus aurantium extract for health sector uses.

Contact Us

Ready to enhance your formulations with high-purity Naringenin 480-41-1? Our technical team is available to discuss your specific requirements and provide sample testing. Contact us at sales02@kangbiotech.com today.