Nobiletin Powder
Active ingredient: Nobiletin
CAS No: 478-01-3
Specification: 98% HPLC
Grade: Food grade
Appearance: White to off-white powder
Package specification: 25kg/drum
Mode of transportation: Express delivery, air transportation, sea transportation
Delivery: sufficient stock, small orders will be shipped via FedEx, while large orders can be shipped by air or by sea.
OEM/ODM: Available
Minimum order quantity: 1kg, samples available
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
High-Purity Nobiletin Powder: Premium Citrus Extract for Nutraceutical & Functional Food Applications
Using innovative ethanol-based purification technology, Kang Biotech produces pharmaceutical-grade Nobiletin Powder with 98% HPLC purity from premium Citrus sinensis L. With 11 years of production experience, our facility spans 33,000 m² and is backed by 20,000,000+ m² of controlled bitter orange farms. Vertical integration guarantees batch-to-batch uniformity and supply chain stability. With 20+ years of citrus extraction experience, our technical team runs 9 ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS-certified production lines. Formulators seeking traceable, compliant polymethoxylated flavonoid constituents will love our offering since every kilogram is quality-checked.
What Is Nobiletin Powder?
The polymethoxylated flavonoid (C28H34O15) Nobiletin Powder is found in citrus peels, especially Citrus sinensis L. (sweet orange). This flavone subclass bioactive chemical has numerous methoxy groups on its flavonoid structure.
Nobiletin is lipophilic, unlike hesperidin. This molecular design improves membrane permeability and bioavailability in lipid-based delivery methods.
Extractions use selected solvents to retain the methoxylation pattern. In completed formulations, molecular integrity determines chemical functionality.
Technical Specifications
| Parameter | Details |
|---|---|
| Botanical Source | Citrus Sinensis L. (Sweet Orange Peel) |
| Active Ingredient | Nobiletin |
| Molecular Formula | C28H34O15 |
| CAS Number | 478-01-3 |
| EINECS Number | 236-216-14 |
| Purity Range | 10%-98% HPLC |
| Standard Grade | 98% HPLC (Food Grade) |
| Appearance | White to Off-White Fine Powder |
| Extraction Method | Water / Ethanol Extraction |
| Moisture Content | ≤5.0% |
| Mesh Size | 80-100 Mesh |
Why Choose Kang Biotech's Nobiletin Extract?
Vertically Integrated Supply Chain
We offer direct access to plantation-level raw materials from our 20,000,000 m² agriculture base. Intermediary markups and supply instability in spot-market sourcing are eliminated.
We have 9 specialized production lines in our 33,000 m² manufacturing facility. Each line follows international food safety guidelines for continual monitoring.
Verified Quality Assurance
Multi-stage ISO 22000 and HACCP laboratory verification is performed on every production batch. Certificates of Analysis verify identification, purity, heavy metals, microbiological load, and pesticide residue.

Our quality documentation supports FDA, EFSA, MHLW, and KFDA regulatory filings. This prevents product launch delays.
Flexible OEM/ODM Options
Need 10%-98% custom purity? R&D works with the Hunan Institute of Agricultural Product Processing to provide formulation-specific standards.
Custom packaging from 1kg foil packets to 25kg fiber drums is available. Multilingual paperwork and regional regulatory declarations are included in private labeling.
Scalable Order Fulfillment
Sample orders from 1kg ship via FedEx within 48 hours from our ready-stock inventory. Optimized maritime freight logistics improve lead times under 30 days for commercial orders above 100kg.
We can produce pilot batches to multi-ton contracts without compromising quality. You keep formulations consistent from R&D to commercialization.
Application Advantages in Product Development
Nutritional Supplements
The lipophilic characteristic of nobiletin makes it suitable for softgel capsules and oil-based delivery matrices. You get better bioavailability than complex-encapsulated water-soluble flavonoids.
Supplements typically include 50-250mg per serving. We use 98% purity to reduce excipient burden and simplify formulas with fewer inactive substances.
Functional Food/Drink
This extract is heat-stable to 180°C and may be pasteurized and spray-dried. Protein bars, drinks, and baked foods can be strengthened without degrading.
At doses below 0.5%, the neutral taste allows clean-label compositions. In most applications, masking agents are unnecessary, simplifying ingredient decks.
Cosmetics & Personal Care
In topical formulations at 0.1-1.0% concentrations, antioxidants support skin wellness claims. Compatible with anhydrous bases and emulsions.
Creams and serums dissolve smoothly with our 80-100 mesh micronized particles. Grittiness from coarser botanical powders is avoided.
Packaging & Logistics
Standard Packaging: 25kg per fiber drum with double food-grade PE liner
Sample Packaging: 1kg aluminum foil bag with resealable closure
Custom Options: 5kg, 10kg, or bulk tote configurations available
Shipping Methods:
Express (1-5kg): FedEx/DHL, 3-7 days globally
Air Freight (6-100kg): 7-12 days to major hubs
Sea Freight (>100kg): 20-35 days, most economical for commercial orders

FAQ
Q: How should the product be kept to stay stable?
A: Store in light-proof containers below 25°C with relative humidity below 60%. For 24 months after manufacture, properly stored material is 98% pure.
Q: Do you give regulatory compliance documentation?
A: Certificate of Analysis, MSDS, allergy statement, GMO-free declaration, and BSE/TSE certifications accompany each shipment. On request, we provide market registration paperwork.
Q: Can purity be adjusted for certain applications?
A: Yes. Based on your cost-performance needs, our R&D team creates custom 10%–98% purity specifications. The minimum bespoke order is 50kg.
Q: What is your average first-order lead time?
A: Stock (98% HPLC, 25kg drums) ships in 2-3 business days. Producing custom specs takes 15-20 days + transportation time depending on location.
Q: Do you provide formulation testing samples?
A: Free 50-100g samples for eligible R&D projects. For sample shipping, contact our staff with application specifics.
Contact Us
Ready to secure stable supply of premium-grade Nobiletin Powder for your next formulation?
Contact our export division today: sales02@kangbiotech.com
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