Polymethoxylated Flavones Citrus Peel
Polymethoxylated Flavones Citrus Peel

Polymethoxylated Flavones Citrus Peel

Production process: Water extraction / Ethanol extraction
Active ingredient: Nobiletin & Tangeretin
Specification: 80% HPLC
Grade: Food grade
Appearance: Powder
Package specification: 25kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Fast global shipping is supported by stable inventory. Shipping methods are selected according to order size, including FedEx for small orders and air or sea freight for bulk purchases.
OEM/ODM: Available
Minimum order quantity: 1kg, samples available
  • Free Samples
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Polymethoxylated Flavones Citrus Peel – High-Purity Citrus Extract for Metabolic & Cognitive Health Applications

Polymethoxylated Flavones Citrus Peel extract from Kang Biotech is pharmaceutical-grade and 80% HPLC pure. Nobiletin and Tangeretin are active indicators. We own 11 years of manufacturing experience and 20,000,000 m² of regulated bitter orange plantations in Lianyuan, Hunan Province. We create citrus bioflavonoids using validated water and ethanol extraction methods. We are ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certified and operate in 33,000 m² with 9 contemporary manufacturing lines. For nutraceutical and functional food applications, our product guarantees batch-to-batch consistency, 10% to 98% purity, and  bioavailability

What Makes Polymethoxylated Flavones Citrus Peel Different?

Polymethoxylated Flavones Citrus Peel has numerous methoxyl groups on its structure, unlike Hesperidin. Lipophilicity and metabolic stability increase with this structural change.

Improved cell membrane permeability. Your formulations gain from bioavailability without high dosages.

Tangeretin, Sinensetin, Isosinensetin, and Nobiletin are chemical markers. Despite heat and pH fluctuations, these compounds remain powerful during production.

Fine, light yellow to greenish-brown powder is extract. Citrusy and woody, it's ideal for encapsulated vitamins and advanced delivery.

Technical Specifications

Parameter Specification
Botanical Source Citrus Sinensis L.
Active Ingredients Nobiletin & Tangeretin
Purity Range 10%-98% HPLC
Standard Grade 80% HPLC
Molecular Formula C₂₀H₂₀O₇
EINECS Number 236-216-13
Appearance Fine powder
Color Light yellow to greenish-brown
Extraction Method Water extraction / Ethanol extraction
Grade Food grade
Package Size 25 kg/drum
MOQ 1 kg (samples available)

Core Applications Across Industries

Metabolic Health Formulations

Our extract improves metabolic syndrome treatments. It regulates lipid metabolism and insulin sensitivity via AMPK pathways. Clinical supplements for blood glucose and cardiovascular health use this approach.

Nootropics & Cognitive Support

Because it crosses the blood-brain barrier, nobiletin is a top brain health ingredient. It supports cognitive lifespan and mental clarity by reducing neuroinflammation and amyloid-beta buildup.

Functioning Beverages

Nano-emulsification makes clear functional beverages despite lipophilicity. Anti-inflammatory and stable after pasteurization, the extract does not compromise taste or appearance.

Nutrition and Recovery in Sports

After-workout formulas benefit from anti-inflammatory effects. Enhanced metabolic efficiency and lower oxidative stress indicators benefit your sports nutrition products.

Quality Control Standards You Can Trust

Our quality assurance methodology covers all important controls:

Nobiletin and Tangeretin ratios are verified by HPLC-DAD Fingerprinting, ensuring botanical source integrity. You'll get real citrus-derived chemicals.

Our Residual Solvent Analysis adheres to USP <467> requirements. To ensure food-grade safety, we test ethanol and ethyl acetate.

The pesticide screening uses GC-MS/MS. Your organophosphate-free supply chain meets California Prop 65 and other regional regulations.

ICP-MS testing includes lead, arsenic, cadmium, and mercury. All batches satisfy worldwide nutraceutical safety standards.

Ultra-high purity batches undergo qNMR Methoxyl Group Verification. The degree of methoxylation influences biological potency.

Quality Control Standards You Can Trust

Manufacturing  & Customization

Continuous innovation comes from our Joint Research Center with the Hunan Institute of Agricultural Product Processing and Quality Safety. Our solutions are tailored to your formulation needs.

Manufacturers offer specification adjustments, purity optimization,  package design, and labeling compliance. Whether you require 50% standardization for cheap formulae or 98% medicinal purity, we adjust manufacturing settings.

Supply Chain Reliability guarantees readiness. We have standard standards in stock and can accommodate 1 kilogram samples to multi-ton commercial shipments.

Trial quantities can be shipped via FedEx, medium volumes by air, or bulk via sea. Our skilled staff manages paperwork and compliance in 40+ countries.

Manufacturing Excellence & Customization

FAQ

Q: How are Polymethoxylated Flavones different from Hesperidin?

A: PMFs are fat-soluble and methoxylated, making them more bioavailable than water-soluble Hesperidin. Formulations require lower doses due to this structural variation.

Q: What dosage aids metabolic health?

A: Industry guidelines prescribe 50mg to 150mg of standardized extract twice day, depending on PMF levels and goals.

Q: How are liquid PMFs stabilized?

A: Although lipophilic, we advocate PEG-free emulsifiers or liposomal administration. These keep beverages clear and prevent precipitation.

Q: How does your extract meet California Prop 65?

A: Yes. Our rigorous heavy metal and pesticide testing processes surpass area safety standards, including Prop 65.

Q: Why is Nobiletin the primary quality marker?

A: Research supports blood-brain barrier penetration most for nobiletin. It is the gold standard for quality verification since it affects circadian rhythms and lipid oxidation.

Contact Us

Ready to integrate premium citrus bioflavonoids into your product line with Polymethoxylated Flavones Citrus Peel? Contact our technical team at sales02@kangbiotech.com for specifications and samples.