Dihydronaringenin
Active ingredient: Phloretin
CAS No: 60-82-2
Specification: 98% HPLC purity
Appearance: White to off-white powder
Package specification: 25 kg fiber drum
Mode of transportation: Courier, air transportation, sea transportation
Delivery: Ready stock ensures fast shipment. Small quantities are shipped by FedEx, while bulk orders are delivered by air or sea.
OEM/ODM: Supported
Minimum order quantity: 1 kg, sample orders accepted.
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Product Introduction
Dihydronaringenin: Premium Cosmetic-Grade Antioxidant from Kang Biotech
Kang Biotech produces pharmaceutical-grade Dihydronaringenin (CAS No. 60-82-2) with 98% HPLC purity from regulated water or ethanol extraction. Established in 2011 with 11+ years of manufacturing expertise, our 33,000 m² facility features 9 modern production lines. Apple and pear peels and root bark contain Phloretin, a polyphenolic substance. Integrated quality systems are ISO 9001, ISO 22000, HACCP, Halal, and Kosher certified. Our product passes strict international cosmetic requirements with a molecular weight of 274.27 g/mol (C15H14O5) and a melting point range of 260°C to 264°C.
What Is Dihydronaringenin?
Our product is a powerful bio-active polyphenol obtained from natural fruits. Modern skincare formulation issues such inadequate transdermal penetration and oxidative instability are addressed.
This chemical enhances molecular penetration, unlike antioxidants. It breaks lipid bilayers to increase co-administered active bioavailability.
High lipophilicity improves cell membrane permeability. This makes it ideal for topical administration systems with ingredient efficacy constraints.
It solves UV-induced environmental stress hyperpigmentation for the cosmetic sector. It protects sepecific formulas against oxidation.
Technical Properties and Specifications
Our cosmetic-grade product demonstrates consistent physicochemical characteristics that ensure reliable formulation performance.
| Parameter | Specification |
|---|---|
| Botanical Source | Peels and root bark of apples and pears |
| CAS Number | 60-82-2 |
| EINECS Number | 200-488-7 |
| Molecular Formula | C15H14O5 |
| Molecular Weight | 274.27 g/mol |
| Purity | 98% HPLC |
| Appearance | White to off-white powder |
| Melting Point | 260°C to 264°C |
| Grade | Cosmetic |
| Package | 25 kg fiber drum |
The compound exhibits a specific UV absorption peak that facilitates precise quality quantification. Its primary advantage lies in inhibiting Matrix Metalloproteinase-1 (MMP-1) and Elastase activity, providing structural defense against collagen breakdown.
Quality Control Standards
Kang Biotech ensures industrial-grade dependability with rigorous testing processes for each product batch.
HPLC is used to test composition to guarantee no contamination from similar chalcones.
ICP-MS testing for Lead, Arsenic, Cadmium, and Mercury fulfills global USP and EP requirements.
Gas Chromatography (GC) shows ethanol or methanol residue compliance with ICH requirements.
Microbial Limits: TAMC and TYMC testing assures stability in watery formulations.
Photostability Testing: Under high UV exposure, we test color integrity and chemical structure for long-term product performance.
Our Joint Research Center with the Hunan Institute of Agricultural Product Processing and Quality Safety promotes quality improvement and innovation.

Application in Cosmetic Formulations
Dihydronaringenin's performance in final goods depends on formulation.
Advanced Brightening Serums: It stabilizes antioxidant networks and inhibits tyrosinase with Vitamin C and Ferulic Acid. Age spots and uneven skin tone are addressed by this combo.
Anti-Aging Creams & Lotions: Reduces MMP-1 activity to preserve collagen. Facial creams, serums, and essences for aged skin can contain it.
Complex, oily skin environments benefit from its sebum regulation and antibacterial effects against P. acnes.
Face Masks: It provides antioxidant protection during rigorous treatment when added to sheet or wash-off masks.
For clinically significant antioxidant and brightening benefits, use 0.5% to 2.0% topically.
Formulation Guidelines and Technical Support
Understanding the compound's hydrophobicity and stability is key to incorporation.
Our product should be pre-dissolved in organic solvents like Propanediol, Ethanol, or DMI before adding to emulsion oil.
Optimize formula pH between 4.0 and 5.5 to minimize oxidation-related discolouration. Stability is improved by adding Disodium EDTA.
Compatibility: The substance reduces inflammation and boosts anti-aging thru several biological pathways with Retinoids.
Keep cold, dark, and dry in sealed containers. Prolonged light and moisture exposure affects the molecule.
To assist you optimize your applications, our technical team offers product selection, application consultancy, and formulation support.
Supply Capability and Customization Services
Kang Biotech keeps stock for speedy shipment to satisfy urgent manufacturing deadlines.
Our minimum order amount is 1 kilogram, and we accept sample orders for testing. FedEx delivers small orders, whereas air or sea freight delivers big items.
OEM/ODM: We tailor product specifications, purity levels, package design, and labeling to brand and regulatory standards.
Global Delivery Network: We offer flexible logistics solutions for 40+ countries and volumes.
Our consistent raw material supply comes from our 20,000,000+ m² citrus orchards in Lianyuan, Hunan Province. Quality and availability are guarantyd by this integrated supply chain.

FAQ
Q: How can I improve formulation water solubility?
A: Before adding to an emulsion's oil phase, dissolve it in organic solvents like Propanediol, Ethanol, or DMI.
Q: Does the product yellow the finished product?
A: While high-purity grade is stable, high pH can cause oxidation. Avoid discolouration by keeping formula pH between 4.0 and 5.5 and adding chelating agents like Disodium EDTA.
Q: What is the recommended dosage for clinical efficacy?
A: For considerable antioxidant and brightening benefits, topical 0.5% to 2.0% is industry norm.
Q: Do Retinoids work with it?
A: It's utilized with Retinoids to reduce inflammation and boost anti-aging thru multiple biological mechanisms.
Q: How should the product be preserved for longevity?
A: Store airtight in cold, dark, dry places. Since light and moisture damage it, HPLC retesting is necessary to ensure stability.
Contact Us
Partner with Kang Biotech for reliable cosmetic-grade Dihydronaringenin backed by comprehensive quality assurance. Contact our team at sales02@kangbiotech.com for samples, technical documentation, or custom solutions.
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