Hesperetin 520-33-2
Active ingredient: Hesperetin
CAS No: 520-33-2
Specification: 98% HPLC
Grade: Food grade
Appearance: Light yellow powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Sufficient stock available. Small orders via FedEx, large orders by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Hesperetin 520-33-2 – Premium Citrus Flavonoid from Kang Biotech
Kang Biotech provides pharmaceutical-grade Hesperetin 520-33-2, a highly pure flavonoid aglycone that is taken from citrus fruits using technology for extraction. Our building is 33,000 m² and handles 20,000,000 m² of bitter orange plantations. We have been making things for over 11 years and extracting citrus fruits for over 20 years. Our product has been certified as Halal, Kosher, ISO 9001, ISO 22000, and other strict worldwide standards. We can get purity levels as high as 98% by HPLC, which means that our products are more bioavailable and always have the same quality for use in nutraceutical, pharmaceutical, and functional food products around the world.
What Makes Our Hesperetin 520-33-2 Different?
Our product is a bioactive aglycone form of hesperidin that has better metabolic efficiency and membrane permeability. In contrast to its glycoside cousin, this molecule is better absorbed by the human gut.
We use both water and ethanol extraction in our production process to keep the active ingredient's natural purity. This makes a light yellow powder that is very stable at high temperatures and attracts fats.
This ingredient comes from plants like orange, lemon, and fingered citron (Citrus medica var. sarcodactylis). It has a mild bitter taste with light floral and woody undertones. This flavor profile means it can be used for a wide range of formulation needs.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 520-33-2 |
| Molecular Formula | C16H14O6 |
| EINECS Number | 236-216-9 |
| Purity | 80%-98% HPLC |
| Appearance | Light yellow powder |
| Melting Point | 226-228°C |
| Moisture Content | ≤1.0% |
| Grade | Food grade / Pharmaceutical grade |
| Packaging | 25 kg/drum |
Core Application Scenarios
To solve your formulation problems, you need ingredients that are stable and work well. Our product meets three very important needs in the business world.
Nutraceutical Formulations: Its ability to help manage cholesterol levels is good for metabolic health products. As a main ingredient, it works reliably in pills, tablets, and powder mixes aimed at health-conscious customers.
Pharmaceutical Synthesis: The molecule is a useful step in the process of making semi-synthetic flavonoids, such as Diosmin. Because it is stable under catalytic hydrogenation and oxidation conditions, it is ideal for making pharmaceuticals for businesses.
Functional Cosmetics: Skincare products that fight aging use its antioxidant qualities to protect cells from damage. The element stays stable in emulsions with pH levels between 4.5 and 7.0, which means it always works the same way when applied to the skin.
Quality Assurance Framework
In five important checking areas, we use thorough quality control procedures. HPLC Purity Analysis makes sure that no related substances are present and confirms the exact concentration levels.
GC-Headspace Residual Solvent Testing makes sure that ICH Q3C rules are followed. According to USP <2232> guidelines, heavy metal screening with ICP-MS looks for Lead, Arsenic, Cadmium, and Mercury.
Monitoring the particle size distribution improves the soluble properties. Microbiological Assays confirm that our Hesperetin 520-33-2 is free of pathogens, which means it can be used safely in the mouth and on the skin.
The Hunan Institute of Agricultural Product Processing and Quality Safety and our Joint Research Center work together to support ongoing innovation. This relationship makes it easy to respond quickly to changing market trends and customer needs.

Formulation Support and Solubility Solutions
For specific manufacturing methods to work, our product needs to be lipophilic. Solubilizers like cyclodextrins or solid dispersion techniques make sure that your product is spread out evenly in water-based systems.
We can help you solve formulation problems by giving you expert paperwork and application advice. Our team helps with optimizing dosages, creating methods for stable testing, and making sure that regulations are followed.
We offer tailored specifications to meet your exact needs, whether you're making metabolic health supplements, pharmaceutical intermediates, or active ingredients for cosmetics. As part of OEM and ODM services, you can change the particle size, purity, and create the package.

Logistics and Supply Capability
We keep enough inventory on hand to ship right away. For fast delivery, small test orders are sent via FedEx. For big business quantities, you can choose between air or sea freight, depending on your budget and time frame.
Our smallest order is only 1 kg, and we offer samples to help you come up with new recipes. This adaptability helps with both research and development projects and full-scale production starts.
Customers from more than 40 countries value our supply line. We offer steady quality and on-time delivery all year long thanks to our 9 modern production lines and direct plantation resources.
Packaging Options
Standard packaging comes in 25 kg fiber drums with two food-safe plastic bags inside. There are custom package options for situations where you need a certain amount of packing or want to brand it.
All of the materials used for packing meet international standards for food safety. We give you a Certificate of Analysis (CoA) and all the paperwork you need to support your quality control processes.

FAQ
Q: How does the product differ from Hesperidin?
A: Hesperetin, the aglycone form without the sugar moiety, has higher gastric bioavailability and metabolic activity than hesperidin.
Q: How should I store to avoid degradation?
A: In sealed containers, store cold, dry, and dark. Duration of light exposure can photo-oxidize the chemical.
Q: Can the product be formulated in water?
A: Due to limited water solubility, cyclodextrins or solid dispersions are needed for uniform distribution.
Q: Are your products non-GMO?
A: Our ingredient comes from natural citrus and is non-GMO-verified by third parties.
Q: How long does the product last?
A: Specified storage allows retests for 24 months from manufacturing.
Contact Us
Ready to experience the quality difference of enterprise-grade Hesperetin 520-33-2? Contact our technical team at sales02@kangbiotech.com for samples, pricing, and customized solutions tailored to your formulation needs.
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