Apigenin 520-36-5
Active ingredient: Apigenin
CAS No: 520-36-5
Specification: 98% HPLC
Grade: Food grade
Appearance: Light yellow to yellow powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Sufficient stock available. Small orders via FedEx, large orders by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Apigenin 520-36-5 – Premium Flavonoid Extract for Nutraceutical & Functional Applications
Advanced ethanol extraction from Citrus aurantium L. yields industrial-grade Apigenin 520-36-5 with 98% HPLC purity from Kang Biotech. Our facility, with 9 approved manufacturing lines and 11 years of experience in citrus-derived bioactives, spans 33,000 m². As certified by ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS, we guaranty batch quality and worldwide regulatory compliance.
Our 20,000,000 m² regulated agriculture ensures traceability from source to delivery. Available stock, flexible OEM/ODM services, and 1 kilogram minimum order quantities enable R&D and commercial production.
What Is Apigenin 520-36-5?
The polyphenol flavone subclass includes our product, a trihydroxyflavone (4',5,7s). Nature produces it in chamomile, celery, and citrus.
It meets industrial expectations for non-toxic neuroprotective agents and stable antioxidants as a standardized bioactive ingredient. Given its well-documented GABAergic circuit and cytokine modulation effects, evidence-based formulations favor it.
The combination of traditional herbal therapy and contemporary pharmacology makes this chemical a useful raw material for nutraceuticals, cosmeceuticals, and pharmaceutical research.
Technical Specifications
| Parameter | Specification |
|---|---|
| Botanical Source | Citrus aurantium L. |
| Active Ingredient | Apigenin |
| CAS Number | 520-36-5 |
| EINECS Number | 236-216-9 |
| Molecular Formula | C₁₅H₁₀O₅ |
| Purity | 98% HPLC |
| Appearance | Light yellow to yellow fine powder |
| Melting Point | 345–350°C |
| Solubility | Soluble in DMSO, ethanol; sparingly soluble in water |
| Moisture Content | ≤1.0% |
| Package | 25 kg/fiber drum |
| Storage | Cool, dark, dry place; sealed container |
| Shelf Life | 24 months under proper storage |
Core Properties & Technical Advantages
Despite being subjected to high processing temperatures, Apigenin 520-36-5 demonstrates outstanding thermal stability. Its 270.24 g/mol molecular weight and lipophilia make it suitable for lipid-based delivery methods.
Potent free radical scavenging and formulation adaptability are key functional features. The compound's blood-brain barrier crossing makes it useful in cognitive health products.
Its compatibility with excipients and stability in complicated emulsions make it excellent for advanced cosmeceutical and nutraceutical formulations. These technical benefits guaranty dependable performance in many applications.
Primary Application Scenarios
Sleep and Relaxation Supplements
Due to its affinity for GABAA receptor benzodiazepine binding sites, this component is essential to night-time recovery compositions. Daily health supplements benefit from its relaxing benefits without manufactured grogginess.
Skincare Innovations
It boosts UV protection and collagen in B2B skincare. Complex emulsions have better antioxidant stability than many traditional alternatives, promoting anti-aging and skin health products.
Pharm R&D
For its capacity to trigger apoptosis and block angiogenesis, oncologists are using this chemical more. The performance of this study compound in multi-drug-resistant cells shows its utility in metabolically difficult situations.
Quality Control & Assurance
Every batch of the product satisfies international standards thru extensive testing by our quality management system.
Purity Verification: HPLC-DAD verifies ≥98.0% concentration with full traceability.
Heavy Metal Screening: ICP-MS Verifies Lead (<0.5ppm), Arsenic (<0.2ppm), and Mercury (<0.1ppm) compliance.
Hexane and methanol extraction solvents are eliminated using gas chromatography (GC).
Microbial Control: With no E. coli or Salmonella, Total Aerobic Microbial Count (TAMC) and pathogen screening fulfill USP/EP criteria.
Laser diffraction testing optimizes particle size (<10 microns) for improving bioavailability in final dose forms.

Manufacturing & Supply Advantages
Kang Biotech's cultivation-to-production supply chain is integrated. Controlled raw material sourcing is available from our 20,000,000 m² bitter orange plants in Lianyuan, Hunan Province
The Hunan Institute of Agricultural Product Processing Joint Research Center advances extraction technology and quality. Together, we can quickly meet changing client needs.
We stock plenty for rapid delivery. Large business orders benefit from efficient air and sea freight, while small orders ship via FedEx for fast turnaround.
Custom specifications, purity levels, packaging design, and labeling are available thru OEM/ODM. With this flexibility, you can fulfill numerous market regulations.

Packaging & Logistics
Standard packaging is 25 kg per fiber drum, designed for safe storage and transportation. Custom packaging solutions are available to meet your specific handling and branding requirements.
We provide flexible logistics options tailored to order size and destination. Express delivery via FedEx ensures rapid sample shipment, while air and sea freight offer cost-effective solutions for bulk orders.
All shipments include complete documentation supporting customs clearance and regulatory compliance in your target markets.

FAQ
Q: Where does your stuff come from mainly?
A: The ingredients in our product come from Citrus aurantium L. and Matricaria chamomilla, which guaranties a bio-identical profile that premium supplement brands like.
Q: How can I make it easier for the chemicals to dissolve in water during formulation?
A: To improve your final goods' solubility and intestine absorption, we suggest liposomal encapsulation or co-solvents such as Polyethylene Glycol (PEG).
Q: Does this item meet international standards for food safety?
A: It is made in facilities that are GMP-certified and also ISO, Halal, and Kosher-certified. These facilities meet all the world standards for food and dietary products.
Q: What are the best conditions for storage?
A: Maintain the items in their original, tightly sealed containers in a cool, dark, and dry place. If maintained properly, the product stays stable for 24 months.
Q: Are there known drug interactions?
A: A CYP2C9 inhibitor, it might change how some medicines are broken down. For consumer-facing products, we suggest putting in the right warnings and checking out regulatory guidelines.
Contact Us
Ready to source high-quality Apigenin 520-36-5 for your formulations? Contact our team at sales02@kangbiotech.com to discuss specifications, request samples, or place your order today.
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