Hesperidin USP Standard

Hesperidin USP Standard – Pharmaceutical-Grade Citrus Bioflavonoid from Kang Biotech

Hesperidin USP Standard from Kang Biotech satisfies USP monograph standards of 90.0% to 102.0% dry hesperidin. Our 11+ years of manufacturing experience and 20+ years in citrus extraction technology assure constant batch quality from our 33,000 m² production facilities and 20,000,000+ m² managed citrus orchards. The recognized choice for pharmaceutical API synthesis and clinical-grade nutraceutical formulations, our USP-grade hesperidin (CAS 520-26-3) undergoes thorough identity testing including IR and TLC and has regulated impurity profiles that exceed generic 90% extracts.

What Makes Hesperidin USP Standard Different?

We provide the purest citrus bioflavonoid. Pharmacy-grade hesperidin meets USP monograph identity, strength, quality, and purity standards, unlike commercial-grade.

The key is regulated impurity profiles. Chromatographic purity testing detects and limits related chemicals, including exogenous flavonoids like Rutin that suggest botanical adulteration. Strong stability and predictable dissolving rates in solid oral dose forms are achieved.

Validated procedures remove solvent residues and preserve the flavanone glycoside structure (C28H34O15) from Citrus aurantium L. Your compositions get consistent therapeutic results without the unpredictability of inferior plant extracts.

Technical Specifications

Primary Applications in High-Stakes Environments

Pharmaceutical API Synthesis is Hesperidin USP Standard's best use. It is the predecessor to Diosmin and Micronized Purified Flavonoid Fraction (MPFF), which treat chronic venous insufficiency and hemorrhoidal disease worldwide.

High-potency antioxidant supplements in standardized nutraceuticals need clinical purity. Our substance synergizes with Vitamin C and other bioflavonoids without interfering with metabolic processes, offering your goods the reliability health-conscious customers want.

Clinical research reference applications depend on batch-to-batch uniformity. Our USP-compliant substance provides reliable, international regulatory-compliant data for pharmacokinetic research and clinical trials.

Functional drinks, nutritional supplements, and wellness products that enhance circulation and antioxidants benefit from the material's stability.

Quality Control That Exceeds Industry Standards

The major vendor qualifying pain points are addressed by our multi-tiered analytical methodology. HPLC test quantifies hesperidin concentration in each batch within the USP 90.0%-102.0% range.

Validated USP chromatographic purity testing detects related chemicals and citrus contaminants. Exogenous flavonoids are detected, ensuring source botanical integrity for downstream applications.

Impurities testing for heavy metals (Lead, Arsenic, Mercury, Cadmium) is conducted using ICP-MS per USP <232>. To avoid harmful processing solvents from affecting final goods, residual solvents are strictly managed under USP <467> Class 2 and 3 limitations.

Microbial enumeration strictly follows USP <61> and <62>, assuring pathogen-free natural-source extracts for pharmaceutical and nutraceutical supply chains. Our plant has ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications.

Why Kang Biotech for Your USP-Grade Hesperidin?

We manage the full citrus manufacturing process as a direct manufacturer. Our comprehensive strategy reduces broker and multi-tier supplier unpredictability and adulteration threats.

Our Joint Research Center with the Hunan Institute of Agricultural Product Processing and Quality Safety improves extraction technology. This R&D allows us to tailor specifications, purity levels, and particle size (micronization) to increase USP-grade material's low inherent solubility.

We have available stock for rapid dispatch and flexible air, sea, and express logistics. Our 9 modern production lines offer steady supply for 1 kg formulation testing or multi-ton commercial quantities.

OEM and ODM services let us meet your regulatory needs in several markets. Our technical staff assists with documentation, application, and formulation throughout product development.

FAQ

Q: What separates it from commercial 90% hesperidin?

A: USP provides greater chemical purity and batch consistency by requiring identification tests (IR, TLC) and rigorous limitations on related compounds that generic grades typically neglect.

Q: How should the product be stored to ensure compliance?

A: Avoid photo-oxidation and moisture absorption by storing in tight, light-resistant containers at regulated room temperature.

Q: Why is the 'Loss on Drying' test important for this ingredient?

A: Hesperidin absorbs moisture. More than 7.0% LOD might cause assay deterioration and stability issues in final product formulations.

Q: Does the product detect Rutin adulteration?

A: Our USP chromatographic purity test detects exogenous flavonoids like Rutin to protect source plant integrity and avoid commercial adulteration.

Q: Do USP standards include micronization?

A: The USP standard establishes chemical purity, however we can alter particle size (micronization) to optimize solubility for your application.

Contact Us

Ready to secure a reliable source for USP-compliant hesperidin with Hesperidin USP Standard? Contact our technical team at sales02@kangbiotech.com for documentation, samples, or custom specifications tailored to your application requirements.