Hesperidin 520-26-3
Active ingredient: Hesperidin
CAS No: 520-26-3
Specification: 98% HPLC
Grade: Food grade
Appearance: Light yellow to grey powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Sufficient stock available. Small orders via FedEx, while large orders can be shipped by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Hesperidin 520-26-3: Premium Citrus Bioflavonoid from Kang Biotech
Kang Biotech provides pharmaceutical-grade Hesperidin 520-26-3, a naturally occurring citrus bioflavonoid derived from premium Citrus Sinensis L. using approved water and ethanol extraction techniques. Experienced in manufacturing for 11 years and managing 20,000,000 m² of citrus orchards, we guaranty consistent and reliable supply. Our ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS-certified product satisfies strict international quality requirements with purity levels up to 98% HPLC. We monitor each manufacturing run with comprehensive quality control systems in our 33,000 m² facility with 9 specialty lines.
What Is Hesperidin 520-26-3?
Citrus leaves, especially Citrus aurantium L. and Citrus sinensis, bear our product, which is a major flavanone glycoside. Hesperetin-7-O-rutinoside (C28H34O15) is an important bioflavonoid for the areas of medicine, nutrition, and useful foods.
These substances improve your compositions with their antioxidants and stability. The chemical lowers the cost of compositions that support circulation, improve vascular health, and act as nutritional supplements. The product fixes problems with absorption and makes sure that the therapy always works by breaking down flavonoid molecules into tiny pieces.
Technical Specifications
| Parameter | Specification |
|---|---|
| Active Ingredient | Hesperidin |
| CAS Number | 520-26-3 |
| EINECS Number | 208-288-1 |
| Botanical Source | Citrus Sinensis L. |
| Molecular Formula | C28H34O15 |
| Molecular Weight | 610.56 g/mol |
| Purity Range | 10%-98% HPLC |
| Standard Specification | 98% HPLC |
| Appearance | Light yellow to grey powder |
| Melting Point | 258-262°C |
| Grade | Food grade / Pharmaceutical grade |
| Production Process | Water extraction / Ethanol extraction |
Physical and Chemical Properties
Understand the product's specific properties before formulating. This chemical is a fine, cream-to-light yellow crystalline powder with thermal stability.
For certain applications, the solubility profile is advantageous. Unlike water, ether, and benzene, dilute alkaline solutions and pyridine dissolve it easily. Designed pH-optimized delivery methods are possible with this feature.
An important benefit is heat stability. The potency of Hesperidin is over 98% during pasteurization and extrusion. It reduces quality problems during high-temperature production in your industrial operations.
Various applications benefit from antioxidant capability. As consumers want plant-based ingredients, this natural bioflavonoid provides clean-label antioxidant protection in functional drinks, nutritional supplements, and topicals.
Quality Control and Compliance
For each batch of Hesperidin 520-26-3, Kang Biotech follows strict quality control processes. Our USP, EP, and ChP-compliant testing ensures your products fulfill worldwide regulations.
HPLC assay verification, impurity profiling for related chemicals like Isocitrin and Neohesperidin, and ICH Q3C-compliant residual solvent analysis are critical quality factors. According to ICP-MS tests, Lead, Arsenic, Cadmium, and Mercury levels are below 10ppm.
Particle size distribution is studied by laser diffraction to optimize medication dissolving rates. Our Citrus aurantium Synephrine safety testing meets DSHEA and EU requirements.
We are ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certified. Enter regulated marketplaces in Europe, North America, Japan, and South Korea with confidence thanks to our complete compliance structure.

Industrial Applications
Pharmaceuticals: MPFF's main API, Hesperidin, promotes vascular health. For Chronic Venous Insufficiency and hemorrhoids, Diosmin reduces capillary resistance.
Supplements contain antioxidants and circulatory assistance. The chemical works alone or with citrus bioflavonoids like Diosmin to make holistic health products.
A natural stabilizer and bitterness adjuster, Hesperidin is utilized in citrus beverages. Clean-label antioxidants reduce lipid peroxidation and retain flavor over time.
Cosmetics: Hesperidin minimizes dark circles and enhances microcirculation. It enhances skin tone in complex lipid-based emulsion systems by stimulating capillaries.
Packaging and Logistics
Standard packaging employs 25 kilogram fiber drums with food-grade inner liners to ensure product integrity during transport. Your handling needs can be met with custom packaging.
Our order amounts range from 1 kilogram samples to full-scale commercial shipments. Small items are shipped by FedEx for fast delivery, while larger volumes use optimum air or sea freight based on timetable and cost.
Trial formulations and continuous manufacturing are delivered on schedule with enough stock. From plantation to final product, our integrated supply chain reduces sourcing risks.

FAQ
Q1: How is product different from Hesperetin?
A: Hesperidin is a sugar-containing glycoside, whereas Hesperetin is an aglycone. Hesperidin's stability benefits your formulations, although Hesperetin has quicker absorption kinetics depending on your application.
Q2: How do you improve liquid formulation water solubility?
A: Industry professionals improve dispersibility by micronizing, lowering particle size below 10μm, or using cyclodextrins. These methods provide homogeneous liquid dosage form distribution.
Q3: Does the product fit vegan and non-GMO standards?
A: Yes. Our non-GMO, vegan-compliant Hesperidin is a plant-derived citrus extract with TSE/BSE free certificates for different diets.
Q4: What is the optimal storage and shelf life?
A: Under cold, dark, and dry circumstances, sealed fiber drums preserve the product's 36-month retest period, ensuring long-term supply stability for your operations.
Q5: How does it perform under high-heat processing?
A: Heat stability allows the chemical to keep over 98% potency throughout food processing pasteurization or extrusion, safeguarding product quality.
Contact Us
Ready to enhance your formulations with premium Hesperidin 520-26-3? Contact us at sales02@kangbiotech.com to discuss your specific requirements.
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