Neohesperidin 13241-33-3
Active ingredient: Neohesperidin
CAS No: 13241-33-3
Specification: 98% HPLC
Grade: Food grade
Appearance: White or off-white powder
Package specification: 25 kg/drum
Mode of transportation: Express delivery, air freight, sea freight
Delivery: Sufficient stock available. Small orders are shipped via FedEx, while large orders can be delivered by air or sea.
OEM/ODM: Available
Minimum order quantity: 1 kg, samples available.
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Neohesperidin 13241-33-3 – Pure Citrus Flavonoid Extract from Kang Biotech
Kang Biotech makes Neohesperidin 13241-33-3, a high-quality flavanone glycoside that is taken from Citrus aurantium (bitter orange) peels professionally. After 11 years of experience in production and 20 years of technical experience in citrus extraction, we can provide standard ingredients that meet the highest quality standards around the world. The managed bitter orange fields that support our 33,000-square-meter building, which has 9 high-tech production lines, cover over 20,000,000 square meters. Consistent batch quality is guarantyd by ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certifications, as well as HPLC-verified purity levels of 98%. Around the world, our product is used as a trusted natural material in pharmaceutical synthesis, nutraceutical formulas, and functional food uses.

What Is Neohesperidin 13241-33-3?
Bitter orange peel provides our product's healthy citrus flavonoid. It also helps generate robust natural sugar Neohesperidin Dihydrochalcone (NHDC).
Its antioxidant and metabolic support capabilities are widely established. It addresses industrial concerns including various ingredients, reliable raw resources, and plant-based bioactives.
Pure, standardized ingredients address performance issues. Consistent formulation efficacy across production batches is crucial.
Product Specifications
| Parameter | Details |
|---|---|
| Botanical Source | Citrus aurantium L. (Bitter Orange) |
| CAS Number | 13241-33-3 |
| EINECS Number | 236-216-9 |
| Molecular Formula | C28H34O15 |
| Molecular Weight | 610.56 g/mol |
| Active Ingredient | Neohesperidin |
| Specification | 10%–98% HPLC |
| Appearance | White or off-white powder |
| Melting Point | 236–238°C |
| Purity (HPLC) | ≥95% or ≥98% |
| Moisture (LOD) | ≤3.0% |
| Optical Rotation | -80° to -90° |
| Grade | Food grade, pharmaceutical grade |
| Packaging | 25 kg/drum (customizable) |
| Shelf Life | 24 months (cool, dry, light-protected) |
Key Technical Properties
Neohesperidin 13241-33-3 is far more stable at high temperatures and works well with a wide range of pH levels (pH 3.0–9.0). Pasteurization, spray drying, and extrusion are all methods that use a lot of heat, but it doesn't break down.
It dissolves easily in both water and ethanol-based systems because of its fine crystalline structure. It is ideal for adding to drinks, emulsions, and medicine formulas because of this.
The compound has a bitter taste, which is different from hesperidin, which has no taste. This quality is necessary for situations where managed bitterness or taste increase is needed.
It's very stable for storage because it has a high melting point and a low moisture content. When handled properly, the bioactivity stays the same for 24 months.
Industrial Applications of Neohesperidin 13241-33-3
Making pharmaceuticals and nutritional supplements
The first step in making Neohesperidin Dihydrochalcone (NHDC) is to make neohesperidin. This change is necessary to make high-intensity natural sweeteners that are used in drug formulations.
In metabolic health supplements, it helps the body use glucose and reduces inflammation. It is made into pills, tablets, and softgels for goods that promote heart and metabolic health.
Beverage & Flavor Modification
Tonic waters, citrus-based drinks, and functional drinks can all use this ingredient as a natural bittering agent. When compared to manufactured options, it gives a cleaner, more constant bitterness.
It can be used in carbonated drinks and energy drinks because it is stable in high-acid environments. Formulators use it to get exact taste combinations without shortening the shelf life of the product.
Making Cosmetics and Skincare Products
Our product is in high-end skin care products because it is a strong antioxidant and skin-conditioning agent. Free radicals are neutralized within complicated emulsion systems, which backs up claims that it can slow down age and make skin brighter.
Because it works well with many makeup bases, it can be easily added to serums, creams, and balms. It helps brands make their products work better and meet customer desire for actives that come from plants.
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Quality Control Standards
To make sure every batch meets international standards, we use a strict five-point quality control system:
Purity Check: High-Performance Liquid Chromatography (HPLC) checks for active ingredients and related chemicals like hesperidin.
ICP-MS testing makes sure that levels of Lead, Arsenic, Cadmium, and Mercury stay below 1.0 ppm, which is required by USP and EP.
Pesticide Residue Screening: Multi-residue analysis (GC-MS/LC-MS) checks that the product meets world safety standards for food and drugs.
Physical Characterization: Laser diffraction finds out how the sizes of particles are spread out. For production, taped density testing makes sure that the flow is just right.
Microbiological Safety: We make sure the product is safe by testing it for Total Plate Count, Yeast/Mold, and the absence of E. coli and Salmonella.
Each batch is given an HPLC sample to prove that it comes from a plant. This is what makes our product different from cheaper alternatives or fake fillers.

Why Choose Kang Biotech?
From growing the citrus to delivering the finished product, our supply chain is fully integrated. Our 20,000,000+ m² plantations provide a stable and traceable source of raw materials.
We meet compliance standards around the world with our ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certificates. Our goods can be used in food, supplements, medicines, and animal feed.

The Hunan Institute of Agricultural Product Processing and Quality Safety and our Joint Research Center are always coming up with new ideas. We offer both OEM and ODM services, which include specific packaging, purity levels, and specs.
We keep a lot of stock that can be sent right away by FedEx, air freight, or sea freight. The smallest amount you can order from us is just 1 kg, and you can try out samples first.
We provide consistent quality, expert support, and flexible transportation solutions to clients in more than 40 countries. In order for you to succeed, we have to do our best.
FAQ
Q: What distinguishes the product from Hesperidin?
A: They vary in sugar moiety but are structurally identical. Neohesperidose makes neohesperidin bitter, whereas rutinose makes it tasteless. This makes Neohesperidin essential for some flavors.
Q: Is the product stable during high-temperature processing?
A: Yes, it's thermally stable. Normal food pasteurization and extrusion do not degrade it.
Q: How should this substance be stored?
A: Keep cold, dry, and away from light and moisture below 25°C. A 24-month shelf life is provided.
Q: Does it meet worldwide food safety standards?
A: When purchased from Kang Biotech, it satisfies FEMA and GRAS standards. ISO and GMP certificates support it.
Q: How is botanical origin verified?
A: Each batch is HPLC fingerprinted to prove Citrus aurantium L. origin. This sets it apart from cheaper equivalents and synthetic adulterants.
Contact Us
Ready to integrate premium Neohesperidin 13241-33-3 into your formulations? Contact our team at sales02@kangbiotech.com for technical specifications, pricing, or sample requests today.
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