Supercritical CO2 Extraction Flavonoid
Active ingredient: Nobiletin & Tangeretin
Specification: 80% HPLC
Grade: Food grade
Appearance: Powder
Package specification: 25kg/drum
Mode of transportation: Courier, air transportation, marine transportation
Delivery: Sufficient inventory allows rapid processing of all orders. FedEx is recommended for low-volume purchases, while air and marine transportation are available for large-scale shipments.
OEM/ODM: Available
Minimum order quantity: 1kg, samples available
- Free Samples
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Supercritical CO2 Extraction Flavonoid - Premium Plant Extract by Kang Biotech
With over 11 years of commercial experience and 20 years of citrus extraction competence, Kang Biotech manufactures Supercritical CO2 Extraction Flavonoid. Over 20,000,000 m² of citrus plantations support our 33,000 m² facility with 9 modern production lines. We supply high-purity flavonoid extracts with specifications ranging from 10% to 98% HPLC, especially 80% HPLC Nobiletin & Tangeretin, processed by water or ethanol extraction procedures. Our manufacture is ISO 9001, ISO 22000, HACCP, Halal, Kosher, and FAMI-QS certified, assuring batch-to-batch consistency.
What is Supercritical CO2 Extraction Flavonoid?
Our product is a breakthrough class of high-purity polyphenolic chemicals extracted from botanical sources at 31.1°C and 73.8 bar. This green solvent method selectively extracts bioactive flavonoids using supercritical fluid's gas-like diffusivity and liquid-like density.
Three industry challenges are addressed by technology. All hexane and methanol residues are removed first. Two, low-temperature processing retains heat-sensitive flavonoid structures. Third, stronger fractionated selectivity concentrates crude extraction-lost flavonoid subgroups.
This makes your goods cleaner, safer, and stronger for demanding applications.
Product Specifications & Technical Parameters
| Parameter | Specification |
|---|---|
| Botanical Source | Citrus Sinensis L. |
| Active Ingredients | Nobiletin & Tangeretin |
| Specification Range | 10%-98% HPLC |
| Standard Specification | 80% HPLC |
| Molecular Formula | C20H20O7 |
| EINECS Number | 236-216-13 |
| Grade | Food Grade |
| Appearance | Fine Powder |
| Moisture Content | <5% |
| Processing Temperature | 35-55°C |
| Package Size | 25kg/Drum |
| Minimum Order | 1kg (Samples Available) |
Key Properties & Technical Advantages
Supercritical CO2 Extraction Flavonoid delivers exceptional chemical integrity and high bioavailability. The controlled processing temperature range of 35-55°C ensures zero oxidative damage. Your extract maintains optimal stability even under storage.
The resulting flavonoid profile exhibits high lipophilic affinity. When needed, food-grade polar modifiers like 5-10% ethanol capture more polar flavonoid fractions. This flexibility allows you to target specific compound groups.
Our extracts feature a clean-label profile with GRAS status. You'll find no heavy metal co-extraction, which is common in traditional solvent methods. Total flavonoid content (TFC) regularly exceeds 80% purity in refined fractions.
The powder offers optimized particle size distribution. This ensures rapid dissolution in your functional formulations. The slight citrus and woody aroma profile enhances sensory characteristics without overpowering your final product.
Rigorous Quality Control Standards
Quality assurance underpins our production. HPLC and UPLC-MS/MS are used for chemical fingerprinting. You may verify the flavonoid profile and quantify marker chemicals using this.
Gas Chromatography (GC) residual solvent testing maintains USP <467> limits for polar modifiers. Our ORAC and DPPH tests verify biological potency.
Moisture content, ICP-MS heavy metal analysis (Pb, As, Cd, Hg), and TAMC/TYMC microbiological limit testing are part of physical examination. All testing fulfills USP and EP pharmacopeia requirements for regulatory assurance.
Each batch is meticulously documented. You get entire COAs with your package.

Diverse Industry Applications
Nutraceutical Formulations
You can incorporate our extracts into high-potency supplements where precise marker compound ratios support cognitive health claims. The bioavailability enhances formulation effectiveness.
Cosmeceutical Products
The high ORAC antioxidant capacity makes this ideal for anti-aging serums. Lipid-solubility allows deep dermal penetration in complex emulsion environments, delivering visible results your customers will notice.
Functional Food & Beverage
Use our extracts as natural preservatives and health enhancers in premium oils and beverages. The absence of solvent off-flavors ensures sensory profile stability under varying pH and UV exposure conditions.
Pharmaceutical Applications
The high purity and consistent quality meet stringent pharmaceutical requirements. You can rely on batch-to-batch reproducibility for regulated products.
Flexible OEM/ODM Customization Services
Kang Biotech provides comprehensive customization to match your specific requirements. We adjust product specifications, purity levels, and packaging design according to your market needs.
You can request custom labeling, formulation support, and specialized testing. Our technical team helps you navigate different regulatory standards across regions.
Whether you need small trial batches or large commercial quantities, our 33,000 m² facility with 9 production lines ensures reliable supply. Ready stock availability enables rapid order processing.
Logistics & Delivery Solutions
We maintain sufficient inventory for quick turnaround. For small orders (1kg-100kg), FedEx provides fast international delivery. Larger shipments benefit from cost-effective air freight or sea transportation.
Our experienced logistics team handles all documentation. You receive tracking information and estimated delivery times upfront. We've successfully shipped to customers in over 40 countries across Europe, North America, Japan, and South Korea.

FAQ
Q: Why does the product need a modifier?
A: Pure CO2 is nonpolar. A modest amount of ethanol (modifier) alters polarity to efficiently extract polar flavonoids while keeping green effects. Flavonoids of both lipophilic and hydrophilic types can be extracted.
Q: Comparing stability to solvent-extracted versions?
A: SC-CO2 functions in an inert environment at low temperatures. This prevents flavonoids from oxidizing, extending shelf life 30-50% over standard extracts. Products remain potent over time.
Q: Is the process scalable for industrial B2B supply?
A: Absolutely. Multi-vessel systems (up to 1000L+) in modern SC-CO2 plants ensure high throughput and batch-to-batch uniformity. Scale smoothly from development batches to commercial manufacturing.
Q: Does the extract contain waxes or chlorophyll?
A: Use pressure-step separation to remove waxes and pigments. The cleaner flavonoid fraction has better organoleptic qualities for your compositions.
Q: What are the cost implications?
A: CO2 recycling lowers operational costs despite larger capital expenditure. Cutting solvent recovery costs makes premium high-purity ingredients affordable.
Contact Us
Ready to elevate your formulations with Supercritical CO2 Extraction Flavonoid? Contact our team at sales02@kangbiotech.com for technical specifications, samples, or custom solutions today.
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