Nobiletin 98%

Nobiletin 98% – Premium Citrus-Derived Polymethoxyflavone from Kang Biotech

Kang Biotech provides pharmaceutical-grade Nobiletin 98%, a very pure polymethoxylated flavonoid isolated from premium orange peel utilizing HPLC-verified methods. Our 11 years of citrus extraction experience and 20,000,000 m² of controlled bitter orange plants provide consistent results and dependable supply. For ISO 9001, ISO 22000, HACCP, Halal, and Kosher certification, the product satisfies strict international requirements. This lipophilic flavone (CAS 478-01-3) from Citrus sinensis, standardized to ≥98% purity by HPLC, shows enhanced membrane permeability and tailored bioactivity for nutraceutical, functional food, and cosmeceutical uses.

What Is Nobiletin 98%?

Polymethoxyflavone purification method peaks with the product. This isolation removes undesirable essential oils and produces repeatable physiological effects, unlike typical citrus extracts with varying flavonoid profiles.

The 98% purity grade provides dose-dependent bioactivity for clinical-grade metabolic and neuroprotective compositions. It eliminates botanical variability to improve product sensory quality and provide high potency for advanced wellness applications.

Formulators can attain therapeutic thresholds with reduced inclusion rates using this concentrated formulation. Your R&D team can precisely load active ingredients for cognitive health and metabolic support solutions.

Technical Specifications

Why Choose Kang Biotech's Nobiletin 98%?

Vertically Integrated Supply Chain

From citrus cultivation to purification, we manage everything. At our 33,000 m² manufacturing facility, 9 modern lines provide stable inventory and prompt order fulfillment. Manufacturer prices are direct and markup-free.

Pharmaceutical-Quality Systems

ALL batches are tested to USP and EC standards. We ensure quality using HPLC-DAD assay verification, ICP-MS elemental analysis, GC-HS residual solvent screening, and USP <61>/<62> microbiological profiling. Your food, supplement, and cosmeceutical formulations exceed worldwide standards.

Collaboration in Advanced R&D

Customized extraction solutions are available from our Hunan Institute of Agricultural Product Processing Joint Research Center. For particle size modification for dissolving or cyclodextrin complexation for aqueous dispersibility, our technical team provides formulation support specific to your product aims.

Adjustable Order Quantity

We accept low-volume trials (1 kilogram) and commercial manufacturing. Before scaling, sample setups verify performance. FedEx ships express, but bigger packages send air or sea freight per your logistical needs.

Core Applications of Nobiletin 98%

Supplements for cognition

This high-purity grade promotes neuroprotective nootropic compositions. Lipophilic nature allows blood-brain barrier penetration, making it fit for mental clarity and cognitive function goods.

Metabolic Health Items

Premium metabolic health supplements easily include Nobiletin 98%. Since customer confidence depends on constant potency, formulators utilize it in glucose homeostasis and lipid metabolism products.

Custom Drug Formulations

High-end dermatological serums use this ingredient since it's compatible with cosmetic additives. For premium skincare lines, 98% purity eliminates formulation interference and preserves product clarity in clear serum bases.

Functional Food Innovation

Fortified drinks and health bars use this component. It improves nutritional profiles with proper emulsification techniques and maintains clean label appeal as 100% plant-derived.

Quality Control & Testing Protocol

Kang Biotech ensures product integrity with multi-tier inspection:

Identity Verification: HPLC-DAD fingerprinting identified six methoxy groups in Nobiletin, differentiating it from Tangeretin.

High-performance liquid chromatography validates ≥98% concentration, with residual polymethoxyflavones quantified < 2%.

ICP-MS identifies trace metals (Pb, As, Hg, Cd) below regulatory limits. European market access depends on pesticide residue screening following EC 396/2005 standards.

To meet pharmaceutical-grade microbiological limitations for nutritional supplements, total plate count, yeast, mold, and pathogen tests are performed.

Laser diffraction particle size measurement ensures uniform dissolving rates, which is critical for hydrophobic molecules.

Packaging & Logistics

Standard Packaging: 25 kg/fiber drum with double-layer food-grade polyethylene liner

Custom Packaging: Available for OEM/ODM orders with your branding requirements

Shipping Options:

• Express (FedEx): 3–7 business days for samples and small orders
• Air Freight: 7–10 days for medium quantities
• Sea Freight: 25–35 days for bulk commercial shipments

Our ready stock ensures rapid order processing. You receive tracking information upon shipment, and our logistics team coordinates customs documentation for smooth international delivery.

FAQ

Q: How effective is the product against Tangeretin?

A: Our product modulates the circadian clock and protects the brain, whereas Tangeretin lowers lipids. Your formulation aims determine the option.

Q: Is the product water-soluble?

A: Lipophilic. Emulsifiers or cyclodextrin complexation promote dispersibility in water. Our technical staff advises on beverage and liquid supplement solubilization.

Q: What is the product's shelf life?

A: The original sealed container keeps it stable for 24–36 months in a cold, dark, dry environment. Storing properly avoids oxidation and preserves potency.

Q: Can vegan goods employ product?

A: Yes, our product is 100% citrus peels with no animal processing assistance. It complements vegan, vegetarian, and clean label positioning.

Q: How can you avoid pesticides?

A: All batches undergo pesticide residue screening to USP <561> or EC 396/2005 norms. Pesticide usage is minimized by regulated cultivation, and thorough testing assures EU and North American compliance.

Contact US

Ready to enhance your product line with pharmaceutical-grade Nobiletin 98%? Reach us at sales02@kangbiotech.com to discuss your project.